Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

Wnt/β-catenin signaling regulates oligodendrocyte (OL) development. Here the authors show that Tcf7l2, a β-catenin transcriptional partner,sequentially interacts with stage-specific partners to coordinate the transitions of differentiation initiation and maturation during OL development.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chuntao Zhao, Yaqi Deng, Lei Liu, Kun Yu, Liguo Zhang, Haibo Wang, Xuelian He, Jincheng Wang, Changqing Lu, Laiman N Wu, Qinjie Weng, Meng Mao, Jianrong Li, Johan H van Es, Mei Xin, Lee Parry, Steven A Goldman, Hans Clevers, Q. Richard Lu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f0426bb84984cb2bac173cddf0948c3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1f0426bb84984cb2bac173cddf0948c3
record_format	dspace
spelling	oai:doaj.org-article:1f0426bb84984cb2bac173cddf0948c32021-12-02T17:32:21ZDual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation10.1038/ncomms108832041-1723https://doaj.org/article/1f0426bb84984cb2bac173cddf0948c32016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10883https://doaj.org/toc/2041-1723Wnt/β-catenin signaling regulates oligodendrocyte (OL) development. Here the authors show that Tcf7l2, a β-catenin transcriptional partner,sequentially interacts with stage-specific partners to coordinate the transitions of differentiation initiation and maturation during OL development.Chuntao ZhaoYaqi DengLei LiuKun YuLiguo ZhangHaibo WangXuelian HeJincheng WangChangqing LuLaiman N WuQinjie WengMeng MaoJianrong LiJohan H van EsMei XinLee ParrySteven A GoldmanHans CleversQ. Richard LuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chuntao Zhao Yaqi Deng Lei Liu Kun Yu Liguo Zhang Haibo Wang Xuelian He Jincheng Wang Changqing Lu Laiman N Wu Qinjie Weng Meng Mao Jianrong Li Johan H van Es Mei Xin Lee Parry Steven A Goldman Hans Clevers Q. Richard Lu Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
description	Wnt/β-catenin signaling regulates oligodendrocyte (OL) development. Here the authors show that Tcf7l2, a β-catenin transcriptional partner,sequentially interacts with stage-specific partners to coordinate the transitions of differentiation initiation and maturation during OL development.
format	article
author	Chuntao Zhao Yaqi Deng Lei Liu Kun Yu Liguo Zhang Haibo Wang Xuelian He Jincheng Wang Changqing Lu Laiman N Wu Qinjie Weng Meng Mao Jianrong Li Johan H van Es Mei Xin Lee Parry Steven A Goldman Hans Clevers Q. Richard Lu
author_facet	Chuntao Zhao Yaqi Deng Lei Liu Kun Yu Liguo Zhang Haibo Wang Xuelian He Jincheng Wang Changqing Lu Laiman N Wu Qinjie Weng Meng Mao Jianrong Li Johan H van Es Mei Xin Lee Parry Steven A Goldman Hans Clevers Q. Richard Lu
author_sort	Chuntao Zhao
title	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
title_short	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
title_full	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
title_fullStr	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
title_full_unstemmed	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
title_sort	dual regulatory switch through interactions of tcf7l2/tcf4 with stage-specific partners propels oligodendroglial maturation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1f0426bb84984cb2bac173cddf0948c3
work_keys_str_mv	AT chuntaozhao dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT yaqideng dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT leiliu dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT kunyu dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT liguozhang dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT haibowang dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT xuelianhe dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT jinchengwang dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT changqinglu dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT laimannwu dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT qinjieweng dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT mengmao dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT jianrongli dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT johanhvanes dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT meixin dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT leeparry dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT stevenagoldman dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT hansclevers dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation AT qrichardlu dualregulatoryswitchthroughinteractionsoftcf7l2tcf4withstagespecificpartnerspropelsoligodendroglialmaturation
_version_	1718380293721686016

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

Ejemplares similares