Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population

Abstract Stool consistency is evaluated mainly in reference to indirect indicators such as water content or the appearance of stool forms using Bristol Stool Form Scale (BSFS). Methods of measurement are limited. We thus aimed to develop a simple protocol for direct measurement of stool consistency...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kazunori Matsuda, Takuya Akiyama, Satoshi Tsujibe, Kaihei Oki, Agata Gawad, Junji Fujimoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1f083e6e0b0b4ad3bf43a826bbfc2798
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1f083e6e0b0b4ad3bf43a826bbfc2798
record_format	dspace
spelling	oai:doaj.org-article:1f083e6e0b0b4ad3bf43a826bbfc27982021-12-02T10:48:31ZDirect measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population10.1038/s41598-021-81783-72045-2322https://doaj.org/article/1f083e6e0b0b4ad3bf43a826bbfc27982021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81783-7https://doaj.org/toc/2045-2322Abstract Stool consistency is evaluated mainly in reference to indirect indicators such as water content or the appearance of stool forms using Bristol Stool Form Scale (BSFS). Methods of measurement are limited. We thus aimed to develop a simple protocol for direct measurement of stool consistency using the TA.XTExpress Texture Analyser (Stable Micro Systems Ltd.). We developed a protocol which enables mechanical quantification of the gram-force against a cylindrical probe (ø 6 mm) pushed into the stool surface at 2.0 mm/s to 5 mm depth. The consistency of 252 stools collected from 40 healthy Belgians was evaluated by the direct method and by the indirect indicators (water content and BSFS) for comparison. The log-transformed stool consistency values measured by the texture analyzer had a negative linear correlation with the stool water contents (r rm = − 0.781) with homoscedastic variance, suggesting the appropriateness of the new protocol. They showed a similar correlation with the BSFS, but with a large variance in the consistency values of normal stool forms. This correlation was much smaller for BSFS scored by subjects (r rm = − 0.587) than by experts (r rm = − 0.789), collectively indicating BSFS as a rough indicator of stool consistency susceptible to subjective bias despite its effectiveness in clinical use. The optimized direct method using the texture analyzer enables the accurate quantification of stool consistency, which facilitates understanding of the intestinal environment and function and thus may enhance the value of the stool as a predictor of human health.Kazunori MatsudaTakuya AkiyamaSatoshi TsujibeKaihei OkiAgata GawadJunji FujimotoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kazunori Matsuda Takuya Akiyama Satoshi Tsujibe Kaihei Oki Agata Gawad Junji Fujimoto Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
description	Abstract Stool consistency is evaluated mainly in reference to indirect indicators such as water content or the appearance of stool forms using Bristol Stool Form Scale (BSFS). Methods of measurement are limited. We thus aimed to develop a simple protocol for direct measurement of stool consistency using the TA.XTExpress Texture Analyser (Stable Micro Systems Ltd.). We developed a protocol which enables mechanical quantification of the gram-force against a cylindrical probe (ø 6 mm) pushed into the stool surface at 2.0 mm/s to 5 mm depth. The consistency of 252 stools collected from 40 healthy Belgians was evaluated by the direct method and by the indirect indicators (water content and BSFS) for comparison. The log-transformed stool consistency values measured by the texture analyzer had a negative linear correlation with the stool water contents (r rm = − 0.781) with homoscedastic variance, suggesting the appropriateness of the new protocol. They showed a similar correlation with the BSFS, but with a large variance in the consistency values of normal stool forms. This correlation was much smaller for BSFS scored by subjects (r rm = − 0.587) than by experts (r rm = − 0.789), collectively indicating BSFS as a rough indicator of stool consistency susceptible to subjective bias despite its effectiveness in clinical use. The optimized direct method using the texture analyzer enables the accurate quantification of stool consistency, which facilitates understanding of the intestinal environment and function and thus may enhance the value of the stool as a predictor of human health.
format	article
author	Kazunori Matsuda Takuya Akiyama Satoshi Tsujibe Kaihei Oki Agata Gawad Junji Fujimoto
author_facet	Kazunori Matsuda Takuya Akiyama Satoshi Tsujibe Kaihei Oki Agata Gawad Junji Fujimoto
author_sort	Kazunori Matsuda
title	Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
title_short	Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
title_full	Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
title_fullStr	Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
title_full_unstemmed	Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population
title_sort	direct measurement of stool consistency by texture analyzer and calculation of reference value in belgian general population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1f083e6e0b0b4ad3bf43a826bbfc2798
work_keys_str_mv	AT kazunorimatsuda directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation AT takuyaakiyama directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation AT satoshitsujibe directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation AT kaiheioki directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation AT agatagawad directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation AT junjifujimoto directmeasurementofstoolconsistencybytextureanalyzerandcalculationofreferencevalueinbelgiangeneralpopulation
_version_	1718396635063517184

Direct measurement of stool consistency by texture analyzer and calculation of reference value in Belgian general population

Ejemplares similares