A geometric approach to characterize the functional identity of single cells

Functional characterisation of single cells is crucial for uncovering the true extent of cellular heterogeneity. Here the authors offer an approach to infer functional identities of cells from their transcriptomes, identify their dominant function, and reconstruct the underlying regulatory networks.

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Detalles Bibliográficos
Autores principales: Shahin Mohammadi, Vikram Ravindra, David F. Gleich, Ananth Grama
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1f15abdf60fc40a6b3faeb20563a711f
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Sumario:Functional characterisation of single cells is crucial for uncovering the true extent of cellular heterogeneity. Here the authors offer an approach to infer functional identities of cells from their transcriptomes, identify their dominant function, and reconstruct the underlying regulatory networks.