A geometric approach to characterize the functional identity of single cells

Functional characterisation of single cells is crucial for uncovering the true extent of cellular heterogeneity. Here the authors offer an approach to infer functional identities of cells from their transcriptomes, identify their dominant function, and reconstruct the underlying regulatory networks.

Guardado en:

Detalles Bibliográficos
Autores principales:	Shahin Mohammadi, Vikram Ravindra, David F. Gleich, Ananth Grama
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f15abdf60fc40a6b3faeb20563a711f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1f15abdf60fc40a6b3faeb20563a711f
record_format	dspace
spelling	oai:doaj.org-article:1f15abdf60fc40a6b3faeb20563a711f2021-12-02T16:49:35ZA geometric approach to characterize the functional identity of single cells10.1038/s41467-018-03933-22041-1723https://doaj.org/article/1f15abdf60fc40a6b3faeb20563a711f2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03933-2https://doaj.org/toc/2041-1723Functional characterisation of single cells is crucial for uncovering the true extent of cellular heterogeneity. Here the authors offer an approach to infer functional identities of cells from their transcriptomes, identify their dominant function, and reconstruct the underlying regulatory networks.Shahin MohammadiVikram RavindraDavid F. GleichAnanth GramaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shahin Mohammadi Vikram Ravindra David F. Gleich Ananth Grama A geometric approach to characterize the functional identity of single cells
description	Functional characterisation of single cells is crucial for uncovering the true extent of cellular heterogeneity. Here the authors offer an approach to infer functional identities of cells from their transcriptomes, identify their dominant function, and reconstruct the underlying regulatory networks.
format	article
author	Shahin Mohammadi Vikram Ravindra David F. Gleich Ananth Grama
author_facet	Shahin Mohammadi Vikram Ravindra David F. Gleich Ananth Grama
author_sort	Shahin Mohammadi
title	A geometric approach to characterize the functional identity of single cells
title_short	A geometric approach to characterize the functional identity of single cells
title_full	A geometric approach to characterize the functional identity of single cells
title_fullStr	A geometric approach to characterize the functional identity of single cells
title_full_unstemmed	A geometric approach to characterize the functional identity of single cells
title_sort	geometric approach to characterize the functional identity of single cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1f15abdf60fc40a6b3faeb20563a711f
work_keys_str_mv	AT shahinmohammadi ageometricapproachtocharacterizethefunctionalidentityofsinglecells AT vikramravindra ageometricapproachtocharacterizethefunctionalidentityofsinglecells AT davidfgleich ageometricapproachtocharacterizethefunctionalidentityofsinglecells AT ananthgrama ageometricapproachtocharacterizethefunctionalidentityofsinglecells AT shahinmohammadi geometricapproachtocharacterizethefunctionalidentityofsinglecells AT vikramravindra geometricapproachtocharacterizethefunctionalidentityofsinglecells AT davidfgleich geometricapproachtocharacterizethefunctionalidentityofsinglecells AT ananthgrama geometricapproachtocharacterizethefunctionalidentityofsinglecells
_version_	1718383263357075456

A geometric approach to characterize the functional identity of single cells

Ejemplares similares