Turning genes into medicines—what have we learned from gene therapy drug development in the past decade?

Gene and cell therapy products approved over the past decade in Europe and North America have provided new therapeutic options for single gene disorders and for hematologic malignancies. Lessons learned, and limitations identified, are reviewed.

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Detalles Bibliográficos
Autor principal: Katherine A. High
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1f171a9d52474522a7b4c78c99203c64
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Descripción
Sumario:Gene and cell therapy products approved over the past decade in Europe and North America have provided new therapeutic options for single gene disorders and for hematologic malignancies. Lessons learned, and limitations identified, are reviewed.