Quality of life in Ecuadorian patients with established rheumatoid arthritis
Maria Intriago, Genessis Maldonado, Jenny Cardenas, Carlos Rios Rheumatology Department, Universidad Espiritu Santo, Guayaquil, EcuadorCorrespondence: Genessis MaldonadoRheumatology Department, Universidad Espirtu Santo, Km 2.5 Vía la Puntilla Samborondón, Guayaquil, EcuadorTel...
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oai:doaj.org-article:1f2195df32424866abfd8b6dd40ef8492021-12-02T04:10:04ZQuality of life in Ecuadorian patients with established rheumatoid arthritis1179-156Xhttps://doaj.org/article/1f2195df32424866abfd8b6dd40ef8492019-09-01T00:00:00Zhttps://www.dovepress.com/quality-of-life-in-ecuadorian-patients-with-established-rheumatoid-art-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XMaria Intriago, Genessis Maldonado, Jenny Cardenas, Carlos Rios Rheumatology Department, Universidad Espiritu Santo, Guayaquil, EcuadorCorrespondence: Genessis MaldonadoRheumatology Department, Universidad Espirtu Santo, Km 2.5 Vía la Puntilla Samborondón, Guayaquil, EcuadorTel +593 1 786 342 4976Email gcmaldonado@uees.edu.ecPurpose: To evaluate quality of life in patients with established rheumatoid arthritis (RA) and identify the factors that negatively affect it.Methods: This was a cross-sectional study with patients with established RA from a rheumatology center in Ecuador. The RA Quality of Life (RAQoL) questionnaire was used to assess QoL and the Health Assessment Questionnaire — disability index (HAQ-DI) questionnaire for functional capacity. In addition, demographics, clinical characteristics, and markers of disease activity were included. Data were analyzed using SPSS 22.Results: Of 186 patients, 89.8% were women, with a mean age of 51 years, 86.6% had symmetrical polyarticular involvement, 40.3% erosions, 46.8% morning stiffness, 46.8% xerophthalmia, and 39.2% fatigue. Depression was the most frequent comorbidity — 42.5%. The mean HAQ-DI score was 0.8, and 26.9% had functional disability. The mean RAQoL score was 7.2. Xerophthalmia, xerostomia, fatigue, morning stiffness, and depression were related to higher scores in the RAQoL (p<0.05). The mean RAQoL was higher in patients with more disease activity and comorbidities (p<0.05). Likewise, patients with functional disability had a mean RAQoL score of 15.6 versus 4.1 in patients without disability (p<0.05). There were positive correlations between RAQoL and ESR, CRP, painful-joint count, swollen-joint count, VAS of pain, and physician assessment (p<0.05).Conclusion: QoL is severely affected in patients with RA. Depression, fatigue, morning stiffness, pain, high disease activity, and disability have a negative effect on QoL in RA. Likewise, patients with more comorbidities and extraarticular manifestations show worse QoL.Keywords: rheumatoid arthritis, quality of life, RaQoL, EcuadorIntriago MMaldonado GCardenas JRios CDove Medical PressarticleRheumatoid Arthritisquality of lifeRaQoLEcuadorDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 11, Pp 199-205 (2019) |
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Rheumatoid Arthritis quality of life RaQoL Ecuador Diseases of the musculoskeletal system RC925-935 |
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Rheumatoid Arthritis quality of life RaQoL Ecuador Diseases of the musculoskeletal system RC925-935 Intriago M Maldonado G Cardenas J Rios C Quality of life in Ecuadorian patients with established rheumatoid arthritis |
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Maria Intriago, Genessis Maldonado, Jenny Cardenas, Carlos Rios Rheumatology Department, Universidad Espiritu Santo, Guayaquil, EcuadorCorrespondence: Genessis MaldonadoRheumatology Department, Universidad Espirtu Santo, Km 2.5 Vía la Puntilla Samborondón, Guayaquil, EcuadorTel +593 1 786 342 4976Email gcmaldonado@uees.edu.ecPurpose: To evaluate quality of life in patients with established rheumatoid arthritis (RA) and identify the factors that negatively affect it.Methods: This was a cross-sectional study with patients with established RA from a rheumatology center in Ecuador. The RA Quality of Life (RAQoL) questionnaire was used to assess QoL and the Health Assessment Questionnaire — disability index (HAQ-DI) questionnaire for functional capacity. In addition, demographics, clinical characteristics, and markers of disease activity were included. Data were analyzed using SPSS 22.Results: Of 186 patients, 89.8% were women, with a mean age of 51 years, 86.6% had symmetrical polyarticular involvement, 40.3% erosions, 46.8% morning stiffness, 46.8% xerophthalmia, and 39.2% fatigue. Depression was the most frequent comorbidity — 42.5%. The mean HAQ-DI score was 0.8, and 26.9% had functional disability. The mean RAQoL score was 7.2. Xerophthalmia, xerostomia, fatigue, morning stiffness, and depression were related to higher scores in the RAQoL (p<0.05). The mean RAQoL was higher in patients with more disease activity and comorbidities (p<0.05). Likewise, patients with functional disability had a mean RAQoL score of 15.6 versus 4.1 in patients without disability (p<0.05). There were positive correlations between RAQoL and ESR, CRP, painful-joint count, swollen-joint count, VAS of pain, and physician assessment (p<0.05).Conclusion: QoL is severely affected in patients with RA. Depression, fatigue, morning stiffness, pain, high disease activity, and disability have a negative effect on QoL in RA. Likewise, patients with more comorbidities and extraarticular manifestations show worse QoL.Keywords: rheumatoid arthritis, quality of life, RaQoL, Ecuador |
format |
article |
author |
Intriago M Maldonado G Cardenas J Rios C |
author_facet |
Intriago M Maldonado G Cardenas J Rios C |
author_sort |
Intriago M |
title |
Quality of life in Ecuadorian patients with established rheumatoid arthritis |
title_short |
Quality of life in Ecuadorian patients with established rheumatoid arthritis |
title_full |
Quality of life in Ecuadorian patients with established rheumatoid arthritis |
title_fullStr |
Quality of life in Ecuadorian patients with established rheumatoid arthritis |
title_full_unstemmed |
Quality of life in Ecuadorian patients with established rheumatoid arthritis |
title_sort |
quality of life in ecuadorian patients with established rheumatoid arthritis |
publisher |
Dove Medical Press |
publishDate |
2019 |
url |
https://doaj.org/article/1f2195df32424866abfd8b6dd40ef849 |
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