Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function
ABSTRACT Invasive fungal infections remain difficult to treat and require novel targeting strategies. The 12-kDa FK506-binding protein (FKBP12) is a ubiquitously expressed peptidyl-prolyl isomerase with considerable homology between fungal pathogens and is thus a prime candidate for future targeting...
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Autores principales: | Nam K. Tonthat, Praveen Rao Juvvadi, Hengshan Zhang, Soo Chan Lee, Ron Venters, Leonard Spicer, William J. Steinbach, Joseph Heitman, Maria A. Schumacher |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/1f23d06b3ca641a5bba16fb5cbec76e2 |
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