Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study

Background and Objective: Cardiovascular diseases and its risk factors, such as diabetes and hyperlipidemia, are common in Indian population. Statin utilization is high across the country and it is important to assess the adherence because it plays an important role in treatment outcome. Statin adhe...

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Autores principales:	Siddhi Umarje, Neha M James, Priti Dave, Asawari Raut, Neha Pandey
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	adherence knowledge lipid reduction patient perception statin Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/1f2691d63f4e497ab8e46536e00e0a6d
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spelling	oai:doaj.org-article:1f2691d63f4e497ab8e46536e00e0a6d2021-11-12T10:10:55ZImpact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study2230-821010.4103/ijem.ijem_120_21https://doaj.org/article/1f2691d63f4e497ab8e46536e00e0a6d2021-01-01T00:00:00Zhttp://www.ijem.in/article.asp?issn=2230-8210;year=2021;volume=25;issue=3;spage=206;epage=210;aulast=Umarjehttps://doaj.org/toc/2230-8210Background and Objective: Cardiovascular diseases and its risk factors, such as diabetes and hyperlipidemia, are common in Indian population. Statin utilization is high across the country and it is important to assess the adherence because it plays an important role in treatment outcome. Statin adherence is not studied well in India. This study aims at measuring the adherence, perception, and knowledge of individuals on statin therapy. Study Design: Cross-sectional observational study on 130 consented individuals visiting a tertiary care teaching hospital. Study was conducted for a duration of 9 months. Methods and Materials: After obtaining approval from the institutional ethics committee the study subjects were assessed for knowledge, perception, and adherence to statin therapy using a systematically developed interview questionnaire. Results: Good adherence was seen in 42.30% patients. Higher proportions of females were reported to have good adherence. Good adherence was observed in patients with a history of coronary heart disease and atorvastatin as monotherapy (P = 0.0029) and fixed dose combination (P = 0.0012), whereas lipid reduction was found directly related to type of adherence. Lack of knowledge, cost, re-fill issues, and adverse effects were some of the barriers identified. Interpretation and Conclusion: Knowledge and patient perception plays a very important role in determining the adherence to statin therapy. A history of coronary heart disease, choice of statin, and cost of therapy are the contributing factors to adherence. Patient counselling and improving the cost-effectiveness of statin therapy can be considered as interventional strategies to overcome adherence issues.Siddhi UmarjeNeha M JamesPriti DaveAsawari RautNeha PandeyWolters Kluwer Medknow Publicationsarticleadherenceknowledgelipid reductionpatient perceptionstatinDiseases of the endocrine glands. Clinical endocrinologyRC648-665Diseases of the digestive system. GastroenterologyRC799-869ENIndian Journal of Endocrinology and Metabolism, Vol 25, Iss 3, Pp 206-210 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	adherence knowledge lipid reduction patient perception statin Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	adherence knowledge lipid reduction patient perception statin Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869 Siddhi Umarje Neha M James Priti Dave Asawari Raut Neha Pandey Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
description	Background and Objective: Cardiovascular diseases and its risk factors, such as diabetes and hyperlipidemia, are common in Indian population. Statin utilization is high across the country and it is important to assess the adherence because it plays an important role in treatment outcome. Statin adherence is not studied well in India. This study aims at measuring the adherence, perception, and knowledge of individuals on statin therapy. Study Design: Cross-sectional observational study on 130 consented individuals visiting a tertiary care teaching hospital. Study was conducted for a duration of 9 months. Methods and Materials: After obtaining approval from the institutional ethics committee the study subjects were assessed for knowledge, perception, and adherence to statin therapy using a systematically developed interview questionnaire. Results: Good adherence was seen in 42.30% patients. Higher proportions of females were reported to have good adherence. Good adherence was observed in patients with a history of coronary heart disease and atorvastatin as monotherapy (P = 0.0029) and fixed dose combination (P = 0.0012), whereas lipid reduction was found directly related to type of adherence. Lack of knowledge, cost, re-fill issues, and adverse effects were some of the barriers identified. Interpretation and Conclusion: Knowledge and patient perception plays a very important role in determining the adherence to statin therapy. A history of coronary heart disease, choice of statin, and cost of therapy are the contributing factors to adherence. Patient counselling and improving the cost-effectiveness of statin therapy can be considered as interventional strategies to overcome adherence issues.
format	article
author	Siddhi Umarje Neha M James Priti Dave Asawari Raut Neha Pandey
author_facet	Siddhi Umarje Neha M James Priti Dave Asawari Raut Neha Pandey
author_sort	Siddhi Umarje
title	Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
title_short	Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
title_full	Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
title_fullStr	Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
title_full_unstemmed	Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study
title_sort	impact of adherence, patient perception, and knowledge to statin therapy – a cross-sectional study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/1f2691d63f4e497ab8e46536e00e0a6d
work_keys_str_mv	AT siddhiumarje impactofadherencepatientperceptionandknowledgetostatintherapyacrosssectionalstudy AT nehamjames impactofadherencepatientperceptionandknowledgetostatintherapyacrosssectionalstudy AT pritidave impactofadherencepatientperceptionandknowledgetostatintherapyacrosssectionalstudy AT asawariraut impactofadherencepatientperceptionandknowledgetostatintherapyacrosssectionalstudy AT nehapandey impactofadherencepatientperceptionandknowledgetostatintherapyacrosssectionalstudy
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Impact of adherence, patient perception, and knowledge to statin therapy – A cross-sectional study

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