Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis

Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis

The role of regulatory cis-elements in carcinogenesis and metastasis in esophageal squamous cell carcinoma remains crucial. Here the authors investigate H3K27ac-marked active enhancer profiles and transcriptomes in different types of esophageal tissues and identify oncogenic events and potential the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bo Ye, Dandan Fan, Weiwei Xiong, Min Li, Jian Yuan, Qi Jiang, Yuting Zhao, Jianxiang Lin, Jie Liu, Yilv Lv, Xiongjun Wang, Zhigang Li, Jianzhong Su, Yunbo Qiao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1f28e58954f6472a90d785799d564ad2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:1f28e58954f6472a90d785799d564ad2
record_format dspace
spelling oai:doaj.org-article:1f28e58954f6472a90d785799d564ad22021-12-02T16:26:32ZOncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis10.1038/s41467-021-24813-22041-1723https://doaj.org/article/1f28e58954f6472a90d785799d564ad22021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24813-2https://doaj.org/toc/2041-1723The role of regulatory cis-elements in carcinogenesis and metastasis in esophageal squamous cell carcinoma remains crucial. Here the authors investigate H3K27ac-marked active enhancer profiles and transcriptomes in different types of esophageal tissues and identify oncogenic events and potential therapeutic targets.Bo YeDandan FanWeiwei XiongMin LiJian YuanQi JiangYuting ZhaoJianxiang LinJie LiuYilv LvXiongjun WangZhigang LiJianzhong SuYunbo QiaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bo Ye
Dandan Fan
Weiwei Xiong
Min Li
Jian Yuan
Qi Jiang
Yuting Zhao
Jianxiang Lin
Jie Liu
Yilv Lv
Xiongjun Wang
Zhigang Li
Jianzhong Su
Yunbo Qiao
Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
description The role of regulatory cis-elements in carcinogenesis and metastasis in esophageal squamous cell carcinoma remains crucial. Here the authors investigate H3K27ac-marked active enhancer profiles and transcriptomes in different types of esophageal tissues and identify oncogenic events and potential therapeutic targets.
format article
author Bo Ye
Dandan Fan
Weiwei Xiong
Min Li
Jian Yuan
Qi Jiang
Yuting Zhao
Jianxiang Lin
Jie Liu
Yilv Lv
Xiongjun Wang
Zhigang Li
Jianzhong Su
Yunbo Qiao
author_facet Bo Ye
Dandan Fan
Weiwei Xiong
Min Li
Jian Yuan
Qi Jiang
Yuting Zhao
Jianxiang Lin
Jie Liu
Yilv Lv
Xiongjun Wang
Zhigang Li
Jianzhong Su
Yunbo Qiao
author_sort Bo Ye
title Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
title_short Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
title_full Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
title_fullStr Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
title_full_unstemmed Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
title_sort oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1f28e58954f6472a90d785799d564ad2
work_keys_str_mv AT boye oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT dandanfan oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT weiweixiong oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT minli oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT jianyuan oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT qijiang oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT yutingzhao oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT jianxianglin oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT jieliu oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT yilvlv oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT xiongjunwang oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT zhigangli oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT jianzhongsu oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
AT yunboqiao oncogenicenhancersdriveesophagealsquamouscellcarcinogenesisandmetastasis
_version_ 1718383979822841856

Ejemplares similares