Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides
ADP-ribosylated peptides are important molecular tools, however, the lack of effective synthetic methods hinders the access to their complex structures. Here, the authors present a biomimetic α-selective ribosylation reaction coupled with click chemistry ultimately providing a two-step modular synth...
Saved in:
Main Authors: | Anlian Zhu, Xin Li, Lili Bai, Gongming Zhu, Yuanyang Guo, Jianwei Lin, Yiwen Cui, Gaofei Tian, Lihe Zhang, Jianji Wang, Xiang David Li, Lingjun Li |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/1f3c4c9b9d4d4c23b09e955f0979915c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
by: Johannes Gregor Matthias Rack, et al.
Published: (2021) -
Wnt pathway activation by ADP-ribosylation
by: Eungi Yang, et al.
Published: (2016) -
The Making and Breaking of Serine-ADP-Ribosylation in the DNA Damage Response
by: Kira Schützenhofer, et al.
Published: (2021) -
HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones
by: Fa-Hui Sun, et al.
Published: (2021) -
Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.
by: Samuel Kasson, et al.
Published: (2021)