Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

The role of macroautophagy in neuronal processes mediating brain maintenance remains enigmatic. Authors show here that impairing autophagy within the major learning related brain center of Drosophila, and not other regions, triggered a form of presynaptic metaplasticity that was invariably connected...

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Autores principales: Anuradha Bhukel, Christine Brigitte Beuschel, Marta Maglione, Martin Lehmann, Gabor Juhász, Frank Madeo, Stephan J. Sigrist
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1f427542d72747999346bfa2f3bdd184
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