NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

p62 is a signaling hub protein that contributes to the control of energy expenditure. Here the authors investigate the relative roles of p62 and a similar protein, NBR1, and show that NBR1 is required for the repression of thermogenesis in adipocytes occurring in the absence of p62.

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Autores principales:	Jianfeng Huang, Juan F. Linares, Angeles Duran, Wenmin Xia, Alan R. Saltiel, Timo D. Müller, Maria T. Diaz-Meco, Jorge Moscat
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f44af61cd1540b195d9f442e64e2d81
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spelling	oai:doaj.org-article:1f44af61cd1540b195d9f442e64e2d812021-12-02T14:58:43ZNBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ10.1038/s41467-021-23085-02041-1723https://doaj.org/article/1f44af61cd1540b195d9f442e64e2d812021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23085-0https://doaj.org/toc/2041-1723p62 is a signaling hub protein that contributes to the control of energy expenditure. Here the authors investigate the relative roles of p62 and a similar protein, NBR1, and show that NBR1 is required for the repression of thermogenesis in adipocytes occurring in the absence of p62.Jianfeng HuangJuan F. LinaresAngeles DuranWenmin XiaAlan R. SaltielTimo D. MüllerMaria T. Diaz-MecoJorge MoscatNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jianfeng Huang Juan F. Linares Angeles Duran Wenmin Xia Alan R. Saltiel Timo D. Müller Maria T. Diaz-Meco Jorge Moscat NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
description	p62 is a signaling hub protein that contributes to the control of energy expenditure. Here the authors investigate the relative roles of p62 and a similar protein, NBR1, and show that NBR1 is required for the repression of thermogenesis in adipocytes occurring in the absence of p62.
format	article
author	Jianfeng Huang Juan F. Linares Angeles Duran Wenmin Xia Alan R. Saltiel Timo D. Müller Maria T. Diaz-Meco Jorge Moscat
author_facet	Jianfeng Huang Juan F. Linares Angeles Duran Wenmin Xia Alan R. Saltiel Timo D. Müller Maria T. Diaz-Meco Jorge Moscat
author_sort	Jianfeng Huang
title	NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
title_short	NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
title_full	NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
title_fullStr	NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
title_full_unstemmed	NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
title_sort	nbr1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through pparγ
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1f44af61cd1540b195d9f442e64e2d81
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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

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