Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease

To explore early alterations and underlying associations of dopamine levels and microstructure in Parkinson’s Disease (PD), Shang et al use a hybrid positron emission tomography (PET)-magnetic resonance imaging (MRI) approach in early stage patients and age-matched controls. Their data implies that...

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Autores principales:	Song’an Shang, Daixin Li, Youyong Tian, Rushuai Li, Hongdong Zhao, Liyun Zheng, Yingdong Zhang, Yu-Chen Chen, Xindao Yin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/1f4b495acc2d4bb190ad819693722078
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spelling	oai:doaj.org-article:1f4b495acc2d4bb190ad8196937220782021-12-02T17:13:15ZHybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease10.1038/s42003-021-02705-x2399-3642https://doaj.org/article/1f4b495acc2d4bb190ad8196937220782021-10-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02705-xhttps://doaj.org/toc/2399-3642To explore early alterations and underlying associations of dopamine levels and microstructure in Parkinson’s Disease (PD), Shang et al use a hybrid positron emission tomography (PET)-magnetic resonance imaging (MRI) approach in early stage patients and age-matched controls. Their data implies that molecular degeneration mediates the effects of microstructural disorganization on motor dysfunction in the early stages of PD.Song’an ShangDaixin LiYouyong TianRushuai LiHongdong ZhaoLiyun ZhengYingdong ZhangYu-Chen ChenXindao YinNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Song’an Shang Daixin Li Youyong Tian Rushuai Li Hongdong Zhao Liyun Zheng Yingdong Zhang Yu-Chen Chen Xindao Yin Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
description	To explore early alterations and underlying associations of dopamine levels and microstructure in Parkinson’s Disease (PD), Shang et al use a hybrid positron emission tomography (PET)-magnetic resonance imaging (MRI) approach in early stage patients and age-matched controls. Their data implies that molecular degeneration mediates the effects of microstructural disorganization on motor dysfunction in the early stages of PD.
format	article
author	Song’an Shang Daixin Li Youyong Tian Rushuai Li Hongdong Zhao Liyun Zheng Yingdong Zhang Yu-Chen Chen Xindao Yin
author_facet	Song’an Shang Daixin Li Youyong Tian Rushuai Li Hongdong Zhao Liyun Zheng Yingdong Zhang Yu-Chen Chen Xindao Yin
author_sort	Song’an Shang
title	Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
title_short	Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
title_full	Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
title_fullStr	Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
title_full_unstemmed	Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease
title_sort	hybrid pet-mri for early detection of dopaminergic dysfunction and microstructural degradation involved in parkinson’s disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1f4b495acc2d4bb190ad819693722078
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Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease

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