Survival of the simplest in microbial evolution

In asexual populations selection at different genomic loci can interfere with each other. Here, using a biophysical model of molecular evolution the authors show that interference results in long-term degradation of molecular function, an effect that strongly depends on genome size.

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Detalles Bibliográficos
Autores principales:	Torsten Held, Daniel Klemmer, Michael Lässig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f4e8bbd1e284068aa7584764a113b9e
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spelling	oai:doaj.org-article:1f4e8bbd1e284068aa7584764a113b9e2021-12-02T16:57:41ZSurvival of the simplest in microbial evolution10.1038/s41467-019-10413-82041-1723https://doaj.org/article/1f4e8bbd1e284068aa7584764a113b9e2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10413-8https://doaj.org/toc/2041-1723In asexual populations selection at different genomic loci can interfere with each other. Here, using a biophysical model of molecular evolution the authors show that interference results in long-term degradation of molecular function, an effect that strongly depends on genome size.Torsten HeldDaniel KlemmerMichael LässigNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Torsten Held Daniel Klemmer Michael Lässig Survival of the simplest in microbial evolution
description	In asexual populations selection at different genomic loci can interfere with each other. Here, using a biophysical model of molecular evolution the authors show that interference results in long-term degradation of molecular function, an effect that strongly depends on genome size.
format	article
author	Torsten Held Daniel Klemmer Michael Lässig
author_facet	Torsten Held Daniel Klemmer Michael Lässig
author_sort	Torsten Held
title	Survival of the simplest in microbial evolution
title_short	Survival of the simplest in microbial evolution
title_full	Survival of the simplest in microbial evolution
title_fullStr	Survival of the simplest in microbial evolution
title_full_unstemmed	Survival of the simplest in microbial evolution
title_sort	survival of the simplest in microbial evolution
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1f4e8bbd1e284068aa7584764a113b9e
work_keys_str_mv	AT torstenheld survivalofthesimplestinmicrobialevolution AT danielklemmer survivalofthesimplestinmicrobialevolution AT michaellassig survivalofthesimplestinmicrobialevolution
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Survival of the simplest in microbial evolution

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