No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.

<h4>Background</h4>Oxytocin (OXT) has been implicated in a suite of complex social behaviors including observed choices in economic laboratory experiments. However, actual studies of associations between oxytocin receptor (OXTR) gene variants and experimentally elicited social preference...

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Autores principales:	Coren L Apicella, David Cesarini, Magnus Johannesson, Christopher T Dawes, Paul Lichtenstein, Björn Wallace, Jonathan Beauchamp, Lars Westberg
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1f4f9ec0d3094dcdb6a88678a2e49e56
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spelling	oai:doaj.org-article:1f4f9ec0d3094dcdb6a88678a2e49e562021-12-02T20:20:46ZNo association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.1932-620310.1371/journal.pone.0011153https://doaj.org/article/1f4f9ec0d3094dcdb6a88678a2e49e562010-06-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20585395/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Oxytocin (OXT) has been implicated in a suite of complex social behaviors including observed choices in economic laboratory experiments. However, actual studies of associations between oxytocin receptor (OXTR) gene variants and experimentally elicited social preferences are rare.<h4>Methodology/principal findings</h4>We test hypotheses of associations between social preferences, as measured by behavior in two economic games, and 9 single nucleotide polymorphisms (SNPs) of the OXTR gene in a sample of Swedish twins (n = 684). Two standard economic games, the dictator game and the trust game, both involving real monetary consequences, were used to elicit such preferences. After correction for multiple hypothesis testing, we found no significant associations between any of the 9 single nucleotide polymorphisms (SNPs) and behavior in either of the games.<h4>Conclusion</h4>We were unable to replicate the most significant association reported in previous research between the amount donated in a dictator game and an OXTR genetic variant.Coren L ApicellaDavid CesariniMagnus JohannessonChristopher T DawesPaul LichtensteinBjörn WallaceJonathan BeauchampLars WestbergPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 5, Iss 6, p e11153 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Coren L Apicella David Cesarini Magnus Johannesson Christopher T Dawes Paul Lichtenstein Björn Wallace Jonathan Beauchamp Lars Westberg No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
description	<h4>Background</h4>Oxytocin (OXT) has been implicated in a suite of complex social behaviors including observed choices in economic laboratory experiments. However, actual studies of associations between oxytocin receptor (OXTR) gene variants and experimentally elicited social preferences are rare.<h4>Methodology/principal findings</h4>We test hypotheses of associations between social preferences, as measured by behavior in two economic games, and 9 single nucleotide polymorphisms (SNPs) of the OXTR gene in a sample of Swedish twins (n = 684). Two standard economic games, the dictator game and the trust game, both involving real monetary consequences, were used to elicit such preferences. After correction for multiple hypothesis testing, we found no significant associations between any of the 9 single nucleotide polymorphisms (SNPs) and behavior in either of the games.<h4>Conclusion</h4>We were unable to replicate the most significant association reported in previous research between the amount donated in a dictator game and an OXTR genetic variant.
format	article
author	Coren L Apicella David Cesarini Magnus Johannesson Christopher T Dawes Paul Lichtenstein Björn Wallace Jonathan Beauchamp Lars Westberg
author_facet	Coren L Apicella David Cesarini Magnus Johannesson Christopher T Dawes Paul Lichtenstein Björn Wallace Jonathan Beauchamp Lars Westberg
author_sort	Coren L Apicella
title	No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
title_short	No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
title_full	No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
title_fullStr	No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
title_full_unstemmed	No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
title_sort	no association between oxytocin receptor (oxtr) gene polymorphisms and experimentally elicited social preferences.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/1f4f9ec0d3094dcdb6a88678a2e49e56
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No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.

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