In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials

Control of denture plaque biofilms is a practical approach to preventing persistent oral infections such as denture stomatitis. Objectives. This study compared in vitro biofilm attachment and growth on a new denture material, Ultaire® AKP, with that on traditional denture materials including cobalt...

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Autores principales:	Cadie Martin, Laura Purevdorj-Gage, Wei Li, Timothy J. Shary, Bin Yang, Ryan J. Murphy, Christine D. Wu
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/1f4fce4669864325969fb4f1b7ce6a7c
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spelling	oai:doaj.org-article:1f4fce4669864325969fb4f1b7ce6a7c2021-11-08T02:36:28ZIn Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials1687-873610.1155/2021/4713510https://doaj.org/article/1f4fce4669864325969fb4f1b7ce6a7c2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/4713510https://doaj.org/toc/1687-8736Control of denture plaque biofilms is a practical approach to preventing persistent oral infections such as denture stomatitis. Objectives. This study compared in vitro biofilm attachment and growth on a new denture material, Ultaire® AKP, with that on traditional denture materials including cobalt chrome (CoCr), polymethyl methacrylate (PMMA), and polyoxymethylene (POM). Methods. Microbial biofilms were grown with cultures of Candida albicans, Streptococcus mutans UA159, or a mixed Streptococcus spp. (S. mutans 700610/Streptococcus sanguinis BAA-1455) for 6 hours in a static protocol or 24 hours in a dynamic protocol for each material. Adherent biofilm cells were removed, and viable colony-forming units (CFUs) were enumerated. Confocal microscopy of the 24-hour Streptococcus spp. biofilms was used to determine biofilm mass and roughness coefficients. Results. The rank order of C. albicans attachment after 6 hours was CoCr > PMMA∗ > Ultaire® AKP∗ (∗vs CoCr, p≤0.05), and that for 24-hour biofilm growth was CoCr > Ultaire® AKP∗ > PMMA∗ (∗vs CoCr, p≤0.05). The rank order of S. mutans biofilm attachment was CoCr > POM > Ultaire® AKP∗ > PMMA∗ (∗vs CoCr, p≤0.05), and that for the 24-hour Streptococcus spp. biofilm growth was POM > Ultaire® AKP > PMMA > CoCr∗ (∗vs POM, p≤0.05). Confocal images revealed structural differences in Streptococcus spp. biofilms on CoCr compared with the other test materials. Significantly lower roughness coefficients of Streptococcus spp. biofilms on Ultaire® AKP were noted, suggesting that these biofilms were less differentiated. Ultaire® AKP promoted significantly less C. albicans and S. mutans biofilm attachment than CoCr at 6 hours and C. albicans growth at 24 hours. Streptococcus spp. biofilms on Ultaire® AKP were less differentiated than those on other test materials. Conclusion. In addition to its material strength, Ultaire® AKP represents an attractive option for denture material in removable partial dentures.Cadie MartinLaura Purevdorj-GageWei LiTimothy J. SharyBin YangRyan J. MurphyChristine D. WuHindawi LimitedarticleDentistryRK1-715ENInternational Journal of Dentistry, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dentistry RK1-715
spellingShingle	Dentistry RK1-715 Cadie Martin Laura Purevdorj-Gage Wei Li Timothy J. Shary Bin Yang Ryan J. Murphy Christine D. Wu In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
description	Control of denture plaque biofilms is a practical approach to preventing persistent oral infections such as denture stomatitis. Objectives. This study compared in vitro biofilm attachment and growth on a new denture material, Ultaire® AKP, with that on traditional denture materials including cobalt chrome (CoCr), polymethyl methacrylate (PMMA), and polyoxymethylene (POM). Methods. Microbial biofilms were grown with cultures of Candida albicans, Streptococcus mutans UA159, or a mixed Streptococcus spp. (S. mutans 700610/Streptococcus sanguinis BAA-1455) for 6 hours in a static protocol or 24 hours in a dynamic protocol for each material. Adherent biofilm cells were removed, and viable colony-forming units (CFUs) were enumerated. Confocal microscopy of the 24-hour Streptococcus spp. biofilms was used to determine biofilm mass and roughness coefficients. Results. The rank order of C. albicans attachment after 6 hours was CoCr > PMMA∗ > Ultaire® AKP∗ (∗vs CoCr, p≤0.05), and that for 24-hour biofilm growth was CoCr > Ultaire® AKP∗ > PMMA∗ (∗vs CoCr, p≤0.05). The rank order of S. mutans biofilm attachment was CoCr > POM > Ultaire® AKP∗ > PMMA∗ (∗vs CoCr, p≤0.05), and that for the 24-hour Streptococcus spp. biofilm growth was POM > Ultaire® AKP > PMMA > CoCr∗ (∗vs POM, p≤0.05). Confocal images revealed structural differences in Streptococcus spp. biofilms on CoCr compared with the other test materials. Significantly lower roughness coefficients of Streptococcus spp. biofilms on Ultaire® AKP were noted, suggesting that these biofilms were less differentiated. Ultaire® AKP promoted significantly less C. albicans and S. mutans biofilm attachment than CoCr at 6 hours and C. albicans growth at 24 hours. Streptococcus spp. biofilms on Ultaire® AKP were less differentiated than those on other test materials. Conclusion. In addition to its material strength, Ultaire® AKP represents an attractive option for denture material in removable partial dentures.
format	article
author	Cadie Martin Laura Purevdorj-Gage Wei Li Timothy J. Shary Bin Yang Ryan J. Murphy Christine D. Wu
author_facet	Cadie Martin Laura Purevdorj-Gage Wei Li Timothy J. Shary Bin Yang Ryan J. Murphy Christine D. Wu
author_sort	Cadie Martin
title	In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
title_short	In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
title_full	In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
title_fullStr	In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
title_full_unstemmed	In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
title_sort	in vitro biofilm formation on aryl ketone polymer (akp), a new denture material, compared with that on three traditional dental denture materials
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/1f4fce4669864325969fb4f1b7ce6a7c
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In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials

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