A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation

A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation

Neuroligins are postsynaptic cell adhesion molecules thought to play roles in synaptic development and function. Here, authors show that phosphorylation of Y782 in neuroligin-1 modulates its role in differentiation and ability to recruit AMPARs including during long-term potentiation.

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Autores principales: Mathieu Letellier, Zsófia Szíber, Ingrid Chamma, Camille Saphy, Ioanna Papasideri, Béatrice Tessier, Matthieu Sainlos, Katalin Czöndör, Olivier Thoumine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1f597343a874478e9252c5ddcfcad8b2
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spelling oai:doaj.org-article:1f597343a874478e9252c5ddcfcad8b22021-12-02T14:40:07ZA unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation10.1038/s41467-018-06220-22041-1723https://doaj.org/article/1f597343a874478e9252c5ddcfcad8b22018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06220-2https://doaj.org/toc/2041-1723Neuroligins are postsynaptic cell adhesion molecules thought to play roles in synaptic development and function. Here, authors show that phosphorylation of Y782 in neuroligin-1 modulates its role in differentiation and ability to recruit AMPARs including during long-term potentiation.Mathieu LetellierZsófia SzíberIngrid ChammaCamille SaphyIoanna PapasideriBéatrice TessierMatthieu SainlosKatalin CzöndörOlivier ThoumineNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mathieu Letellier
Zsófia Szíber
Ingrid Chamma
Camille Saphy
Ioanna Papasideri
Béatrice Tessier
Matthieu Sainlos
Katalin Czöndör
Olivier Thoumine
A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
description Neuroligins are postsynaptic cell adhesion molecules thought to play roles in synaptic development and function. Here, authors show that phosphorylation of Y782 in neuroligin-1 modulates its role in differentiation and ability to recruit AMPARs including during long-term potentiation.
format article
author Mathieu Letellier
Zsófia Szíber
Ingrid Chamma
Camille Saphy
Ioanna Papasideri
Béatrice Tessier
Matthieu Sainlos
Katalin Czöndör
Olivier Thoumine
author_facet Mathieu Letellier
Zsófia Szíber
Ingrid Chamma
Camille Saphy
Ioanna Papasideri
Béatrice Tessier
Matthieu Sainlos
Katalin Czöndör
Olivier Thoumine
author_sort Mathieu Letellier
title A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
title_short A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
title_full A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
title_fullStr A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
title_full_unstemmed A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
title_sort unique intracellular tyrosine in neuroligin-1 regulates ampa receptor recruitment during synapse differentiation and potentiation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1f597343a874478e9252c5ddcfcad8b2
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