Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report

A 56-year-old female patient was presented with abdominal distension and decreased appetite. Diagnosis confirmed breast cancer, a mastectomy, and multiple lines of chemotherapy. Later on, the patient developed liver metastasis and received whole liver radiotherapy (WLRT) for diffuse liver metastasis...

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Autores principales:	Prakash Pandit, Vijay Palwe, Roshankumar Patil, Raj Nagarkar
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2021
Materias:	radiotherapy whole liver irradiation liver metastasis quality of life palliative care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/1f5d2a00696a4a86aa634adc62d75a0f
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spelling	oai:doaj.org-article:1f5d2a00696a4a86aa634adc62d75a0f2021-11-29T10:40:47ZWhole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report2008-67092008-668710.30476/mejc.2020.84968.1248https://doaj.org/article/1f5d2a00696a4a86aa634adc62d75a0f2021-10-01T00:00:00Zhttps://mejc.sums.ac.ir/article_47050_5bbacf7d6eaed75de961d89840f2bb7c.pdfhttps://doaj.org/toc/2008-6709https://doaj.org/toc/2008-6687A 56-year-old female patient was presented with abdominal distension and decreased appetite. Diagnosis confirmed breast cancer, a mastectomy, and multiple lines of chemotherapy. Later on, the patient developed liver metastasis and received whole liver radiotherapy (WLRT) for diffuse liver metastasis. This phenomenon is still the most prevalent site of metastases, particularly in lung, breast, and gastrointestinal cancers owing to its rich, dual blood supply and its role as a filter in the portal circulation. Conventional treatment approaches are not effective in such patients due to diffuse liver involvement; thus, the use of low-dose WLRT is considered as a good alternative. In practice, palliative liver irradiation is a rare modality due to radiationinduced hepatitis. However, WLRT treatment aims at the palliation of symptoms and improving the patients’ quality of life rather than enhancing survival. Results of the present case report also showed that WLRT in patients with poor performance status would ultimately improve their palliative symptoms and overall quality of life with acceptable morbidity.Prakash PanditVijay PalweRoshankumar PatilRaj NagarkarShiraz University of Medical Sciencesarticleradiotherapywhole liver irradiationliver metastasisquality of lifepalliative careNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENMiddle East Journal of Cancer , Vol 12, Iss 4, Pp 608-612 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiotherapy whole liver irradiation liver metastasis quality of life palliative care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	radiotherapy whole liver irradiation liver metastasis quality of life palliative care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Prakash Pandit Vijay Palwe Roshankumar Patil Raj Nagarkar Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
description	A 56-year-old female patient was presented with abdominal distension and decreased appetite. Diagnosis confirmed breast cancer, a mastectomy, and multiple lines of chemotherapy. Later on, the patient developed liver metastasis and received whole liver radiotherapy (WLRT) for diffuse liver metastasis. This phenomenon is still the most prevalent site of metastases, particularly in lung, breast, and gastrointestinal cancers owing to its rich, dual blood supply and its role as a filter in the portal circulation. Conventional treatment approaches are not effective in such patients due to diffuse liver involvement; thus, the use of low-dose WLRT is considered as a good alternative. In practice, palliative liver irradiation is a rare modality due to radiationinduced hepatitis. However, WLRT treatment aims at the palliation of symptoms and improving the patients’ quality of life rather than enhancing survival. Results of the present case report also showed that WLRT in patients with poor performance status would ultimately improve their palliative symptoms and overall quality of life with acceptable morbidity.
format	article
author	Prakash Pandit Vijay Palwe Roshankumar Patil Raj Nagarkar
author_facet	Prakash Pandit Vijay Palwe Roshankumar Patil Raj Nagarkar
author_sort	Prakash Pandit
title	Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
title_short	Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
title_full	Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
title_fullStr	Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
title_full_unstemmed	Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report
title_sort	whole liver radiotherapy- an underutilized weapon for diffuse liver metastasis: a case report
publisher	Shiraz University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/1f5d2a00696a4a86aa634adc62d75a0f
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Whole Liver Radiotherapy- An Underutilized Weapon for Diffuse Liver Metastasis: A Case Report

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