Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods

Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods

Abstract We investigated whether machine learning methods could potentially identify a subgroup of persons with autism spectrum disorder (ASD) who show vitamin B6 responsiveness by selected phenotype variables. We analyzed the existing data from our intervention study with 17 persons. First, we focu...

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Main Authors: Taku Obara, Mami Ishikuro, Gen Tamiya, Masao Ueki, Chizuru Yamanaka, Satoshi Mizuno, Masahiro Kikuya, Hirohito Metoki, Hiroko Matsubara, Masato Nagai, Tomoko Kobayashi, Machiko Kamiyama, Mikako Watanabe, Kazuhiko Kakuta, Minami Ouchi, Aki Kurihara, Naru Fukuchi, Akihiro Yasuhara, Masumi Inagaki, Makiko Kaga, Shigeo Kure, Shinichi Kuriyama
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Autism Spectrum Disorder
Pyridoxine Responsiveness
Selectable Phenotypic Variation
Plasma Glutamine Levels
Conducted Hypothesis Testing
Medicine
R
Science
Q
Online Access:https://doaj.org/article/1f5f4b7d0ff14717814b4720f3836f62
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https://doaj.org/article/1f5f4b7d0ff14717814b4720f3836f62

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