Study on the prognosis predictive model of COVID-19 patients based on CT radiomics

Abstract Making timely assessments of disease progression in patients with COVID-19 could help offer the best personalized treatment. The purpose of this study was to explore an effective model to predict the outcome of patients with COVID-19. We retrospectively included 188 patients (124 in the tra...

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Autores principales: Dandan Wang, Chencui Huang, Siyu Bao, Tingting Fan, Zhongqi Sun, Yiqiao Wang, Huijie Jiang, Song Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1f65b776d63e4385ae2988ad3bc74504
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spelling oai:doaj.org-article:1f65b776d63e4385ae2988ad3bc745042021-12-02T18:25:04ZStudy on the prognosis predictive model of COVID-19 patients based on CT radiomics10.1038/s41598-021-90991-02045-2322https://doaj.org/article/1f65b776d63e4385ae2988ad3bc745042021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90991-0https://doaj.org/toc/2045-2322Abstract Making timely assessments of disease progression in patients with COVID-19 could help offer the best personalized treatment. The purpose of this study was to explore an effective model to predict the outcome of patients with COVID-19. We retrospectively included 188 patients (124 in the training set and 64 in the test set) diagnosed with COVID-19. Patients were divided into aggravation and improvement groups according to the disease progression. Three kinds of models were established, including the radiomics, clinical, and combined model. Receiver operating characteristic curves, decision curves, and Delong’s test were used to evaluate and compare the models. Our analysis showed that all the established prediction models had good predictive performance in predicting the progress and outcome of COVID-19.Dandan WangChencui HuangSiyu BaoTingting FanZhongqi SunYiqiao WangHuijie JiangSong WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Dandan Wang
Chencui Huang
Siyu Bao
Tingting Fan
Zhongqi Sun
Yiqiao Wang
Huijie Jiang
Song Wang
Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
description Abstract Making timely assessments of disease progression in patients with COVID-19 could help offer the best personalized treatment. The purpose of this study was to explore an effective model to predict the outcome of patients with COVID-19. We retrospectively included 188 patients (124 in the training set and 64 in the test set) diagnosed with COVID-19. Patients were divided into aggravation and improvement groups according to the disease progression. Three kinds of models were established, including the radiomics, clinical, and combined model. Receiver operating characteristic curves, decision curves, and Delong’s test were used to evaluate and compare the models. Our analysis showed that all the established prediction models had good predictive performance in predicting the progress and outcome of COVID-19.
format article
author Dandan Wang
Chencui Huang
Siyu Bao
Tingting Fan
Zhongqi Sun
Yiqiao Wang
Huijie Jiang
Song Wang
author_facet Dandan Wang
Chencui Huang
Siyu Bao
Tingting Fan
Zhongqi Sun
Yiqiao Wang
Huijie Jiang
Song Wang
author_sort Dandan Wang
title Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
title_short Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
title_full Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
title_fullStr Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
title_full_unstemmed Study on the prognosis predictive model of COVID-19 patients based on CT radiomics
title_sort study on the prognosis predictive model of covid-19 patients based on ct radiomics
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1f65b776d63e4385ae2988ad3bc74504
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