Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Abstract There is evidence that the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel is highly expressed at the apical pole of ciliated cells in human bronchial epithelium (HBE), however recent studies have detected little CFTR mRNA in those cells. To understand this discrepa...

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Autores principales: Yukiko Sato, Kamila R. Mustafina, Yishan Luo, Carolina Martini, David Y. Thomas, Paul W. Wiseman, John W. Hanrahan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1f668e4b5e9b420599dbb88a96c392a3
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