Update on entecavir in the management of severe forms of Hepatitis B

Rodolfo SaccoDepartment of Gastroenterology, Pisa University Hospital, Pisa, ItalyAbstract: Despite the effective management of most cases of hepatitis B virus (HBV) infection, there is still much room for improvement in the treatment of more severe cases of hepatitis B, such as those occurring in p...

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Autor principal:	Sacco R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/1f695d8e497146bf9033581d82ee1adf
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spelling	oai:doaj.org-article:1f695d8e497146bf9033581d82ee1adf2021-12-02T07:57:37ZUpdate on entecavir in the management of severe forms of Hepatitis B1179-1535https://doaj.org/article/1f695d8e497146bf9033581d82ee1adf2012-05-01T00:00:00Zhttp://www.dovepress.com/update-on-entecavir-in-the-management-of-severe-forms-of-hepatitis-b-a9905https://doaj.org/toc/1179-1535Rodolfo SaccoDepartment of Gastroenterology, Pisa University Hospital, Pisa, ItalyAbstract: Despite the effective management of most cases of hepatitis B virus (HBV) infection, there is still much room for improvement in the treatment of more severe cases of hepatitis B, such as those occurring in patients with decompensated cirrhosis, in transplanted subjects, and in patients with exacerbations of HBV infection. Among the treatments currently approved for the therapy of hepatitis B, entecavir determines a rapid suppression of viral load. This drug is also associated with a high genetic barrier and an overall favorable safety profile. This review provides an overview of recent evidence related to the use of entecavir in the management of the most severe forms of hepatitis B. The results obtained for this drug in real-life clinical practice are also reviewed.Keywords: entecavir, HBV, hepatitis B, chronic hepatitisSacco RDove Medical PressarticleDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol 2012, Iss default, Pp 39-47 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Diseases of the digestive system. Gastroenterology RC799-869 Sacco R Update on entecavir in the management of severe forms of Hepatitis B
description	Rodolfo SaccoDepartment of Gastroenterology, Pisa University Hospital, Pisa, ItalyAbstract: Despite the effective management of most cases of hepatitis B virus (HBV) infection, there is still much room for improvement in the treatment of more severe cases of hepatitis B, such as those occurring in patients with decompensated cirrhosis, in transplanted subjects, and in patients with exacerbations of HBV infection. Among the treatments currently approved for the therapy of hepatitis B, entecavir determines a rapid suppression of viral load. This drug is also associated with a high genetic barrier and an overall favorable safety profile. This review provides an overview of recent evidence related to the use of entecavir in the management of the most severe forms of hepatitis B. The results obtained for this drug in real-life clinical practice are also reviewed.Keywords: entecavir, HBV, hepatitis B, chronic hepatitis
format	article
author	Sacco R
author_facet	Sacco R
author_sort	Sacco R
title	Update on entecavir in the management of severe forms of Hepatitis B
title_short	Update on entecavir in the management of severe forms of Hepatitis B
title_full	Update on entecavir in the management of severe forms of Hepatitis B
title_fullStr	Update on entecavir in the management of severe forms of Hepatitis B
title_full_unstemmed	Update on entecavir in the management of severe forms of Hepatitis B
title_sort	update on entecavir in the management of severe forms of hepatitis b
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/1f695d8e497146bf9033581d82ee1adf
work_keys_str_mv	AT saccor updateonentecavirinthemanagementofsevereformsofhepatitisb
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Update on entecavir in the management of severe forms of Hepatitis B

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