Factors to Consider When Determining Whether Lipotoxicity Solely Causes B-Cell Decompensation in KPT2D [Letter]

Dan Geltser Imperial College London, School of Medicine, London, UKCorrespondence: Dan GeltserImperial College London, School of Medicine, London, UKEmail dg1116@ic.ac.uk I read with great interest the paper by Ye et al,1 which identified the significance of raised triglycerides in the trea...

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Autor principal: Geltser D
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
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Acceso en línea:https://doaj.org/article/1f703038a51b4d8d91e8ea1a34355fe3
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Sumario:Dan Geltser Imperial College London, School of Medicine, London, UKCorrespondence: Dan GeltserImperial College London, School of Medicine, London, UKEmail dg1116@ic.ac.uk I read with great interest the paper by Ye et al,1 which identified the significance of raised triglycerides in the treatment of ketosis-prone type 2 diabetes (KPT2D). The study concluded the need to implement lifestyle changes and administration of lipid-lowering medication for paediatric, hyperglycaemic KPT2D patients. As a 5th year medical student, who completed an intercalated BSc focusing on lipidology in diabetes mellitus, I would like to discuss further factors which should be considered when evaluating the conclusion.   View the original paper by Ye and colleagues