Protein-protein binding selectivity and network topology constrain global and local properties of interface binding networks
Abstract Protein-protein interactions networks (PPINs) are known to share a highly conserved structure across all organisms. What is poorly understood, however, is the structure of the child interface interaction networks (IINs), which map the binding sites proteins use for each interaction. In this...
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Autores principales: | David O. Holland, Benjamin H. Shapiro, Pei Xue, Margaret E. Johnson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1f7e0bc6a42e477ca0376c7ad633ba17 |
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