Protein-protein binding selectivity and network topology constrain global and local properties of interface binding networks

Abstract Protein-protein interactions networks (PPINs) are known to share a highly conserved structure across all organisms. What is poorly understood, however, is the structure of the child interface interaction networks (IINs), which map the binding sites proteins use for each interaction. In this...

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Autores principales: David O. Holland, Benjamin H. Shapiro, Pei Xue, Margaret E. Johnson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1f7e0bc6a42e477ca0376c7ad633ba17
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