Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability

Michael Abrouk,1 Ethan Levin,2 Merrick Brodsky,1 Jessica R Gandy,1 Mio Nakamura,2 Tian Hao Zhu,3 Benjamin Farahnik,4 John Koo,2 Tina Bhutani2 1Irvine School of Medicine, Irvine, 2Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco...

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Autores principales:	Abrouk M, Levin E, Brodsky M, Gandy JR, Nakamura M, Zhu TH, Farahnik B, Koo J, Bhutani T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	excimer laser 308nm psoriasis safety efficacy Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/1f807c56cbd3448f83c6eb38c36dad34
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spelling	oai:doaj.org-article:1f807c56cbd3448f83c6eb38c36dad342021-12-02T07:40:44ZExcimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability2230-326Xhttps://doaj.org/article/1f807c56cbd3448f83c6eb38c36dad342016-12-01T00:00:00Zhttps://www.dovepress.com/excimer-laser-for-the-treatment-of-psoriasis-safety-efficacy-and-patie-peer-reviewed-article-PTThttps://doaj.org/toc/2230-326XMichael Abrouk,1 Ethan Levin,2 Merrick Brodsky,1 Jessica R Gandy,1 Mio Nakamura,2 Tian Hao Zhu,3 Benjamin Farahnik,4 John Koo,2 Tina Bhutani2 1Irvine School of Medicine, Irvine, 2Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco, 3Department of Dermatology, University of Southern California Keck School of Medicine, Los Angeles, CA, 4Department of Dermatology, University of Vermont College of Medicine, Burlington, VT, USA Introduction: The 308 nm excimer laser is a widely used device throughout the field of dermatology for many diseases including psoriasis. Although the laser has demonstrated clinical efficacy, there is a lack of literature outlining the safety, efficacy, and patient acceptability of the excimer laser. Methods: A literature search on PubMed was used with combinations of the terms “excimer”, “excimer laser”, “308 nm”, “psoriasis”, “protocol”, “safety”, “efficacy”, acceptability”, “side effects”, and “dose”. The search results were included if they contained information pertaining to excimer laser and psoriasis treatment and description of the safety, efficacy, and patient acceptability of the treatment. Results: The 308 nm excimer laser is generally safe and well tolerated with minimal side effects including erythema, blistering, and pigmentary changes. It has a range of efficacies depending on the protocol used with several different treatment protocols, including the induration protocol, the minimal erythema dose protocol, and the newer minimal blistering dose protocol. Conclusion: Although the excimer laser is not a first-line treatment, it remains an excellent treatment option for psoriasis patients and has been demonstrated to be an effective treatment with little to no side effects. Keywords: excimer, laser, 308 nm, psoriasis, safety, efficacyAbrouk MLevin EBrodsky MGandy JRNakamura MZhu THFarahnik BKoo JBhutani TDove Medical Pressarticleexcimerlaser308nmpsoriasissafetyefficacyDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol Volume 6, Pp 165-173 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	excimer laser 308nm psoriasis safety efficacy Dermatology RL1-803
spellingShingle	excimer laser 308nm psoriasis safety efficacy Dermatology RL1-803 Abrouk M Levin E Brodsky M Gandy JR Nakamura M Zhu TH Farahnik B Koo J Bhutani T Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
description	Michael Abrouk,1 Ethan Levin,2 Merrick Brodsky,1 Jessica R Gandy,1 Mio Nakamura,2 Tian Hao Zhu,3 Benjamin Farahnik,4 John Koo,2 Tina Bhutani2 1Irvine School of Medicine, Irvine, 2Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco, 3Department of Dermatology, University of Southern California Keck School of Medicine, Los Angeles, CA, 4Department of Dermatology, University of Vermont College of Medicine, Burlington, VT, USA Introduction: The 308 nm excimer laser is a widely used device throughout the field of dermatology for many diseases including psoriasis. Although the laser has demonstrated clinical efficacy, there is a lack of literature outlining the safety, efficacy, and patient acceptability of the excimer laser. Methods: A literature search on PubMed was used with combinations of the terms “excimer”, “excimer laser”, “308 nm”, “psoriasis”, “protocol”, “safety”, “efficacy”, acceptability”, “side effects”, and “dose”. The search results were included if they contained information pertaining to excimer laser and psoriasis treatment and description of the safety, efficacy, and patient acceptability of the treatment. Results: The 308 nm excimer laser is generally safe and well tolerated with minimal side effects including erythema, blistering, and pigmentary changes. It has a range of efficacies depending on the protocol used with several different treatment protocols, including the induration protocol, the minimal erythema dose protocol, and the newer minimal blistering dose protocol. Conclusion: Although the excimer laser is not a first-line treatment, it remains an excellent treatment option for psoriasis patients and has been demonstrated to be an effective treatment with little to no side effects. Keywords: excimer, laser, 308 nm, psoriasis, safety, efficacy
format	article
author	Abrouk M Levin E Brodsky M Gandy JR Nakamura M Zhu TH Farahnik B Koo J Bhutani T
author_facet	Abrouk M Levin E Brodsky M Gandy JR Nakamura M Zhu TH Farahnik B Koo J Bhutani T
author_sort	Abrouk M
title	Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
title_short	Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
title_full	Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
title_fullStr	Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
title_full_unstemmed	Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
title_sort	excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/1f807c56cbd3448f83c6eb38c36dad34
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Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability

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