Healing of cutaneous wounds using GaAs laser in diabetic rat models

Conventional treatment modalities usually fail to heal wounds in diabetic animals. Photomodulation of the wound bed using low-level laser has proved its efficacy in treating chronic wounds. Considering the fact that the majority of the diabetic wounds end up in amputation of affected part and reduce...

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Autores principales: P. Nekha Krishnan, P. T. Dinesh, S. Sooryadas, Reji Varghese, M. Pradeep
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Publicado: Director of Academics and Research, Kerala Veterinary and Animal Sciences University 2021
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spelling oai:doaj.org-article:1f8b700c56ee40d7b4d7b04ea74fa3ca2021-11-15T13:19:43ZHealing of cutaneous wounds using GaAs laser in diabetic rat models10.51966/jvas.2021.52.3.234-2370971-07012582-0605https://doaj.org/article/1f8b700c56ee40d7b4d7b04ea74fa3ca2021-07-01T00:00:00Zhttps://www.jvas.in/public_html/upload/article_file/article_file_r0qhrv.pdf?t=r0qhrvhttps://doaj.org/toc/0971-0701https://doaj.org/toc/2582-0605Conventional treatment modalities usually fail to heal wounds in diabetic animals. Photomodulation of the wound bed using low-level laser has proved its efficacy in treating chronic wounds. Considering the fact that the majority of the diabetic wounds end up in amputation of affected part and reduce the quality of life of the patient, the present study was undertaken to find out the efficacy of gallium arsenide (GaAs) laser in the healing of full-thickness cutaneous wounds in type 2 diabetic rat models. The study was conducted in six adult male Wistar rats with an average body weight of 150 g in which hyperglycemia coexisting with hyperlipidemia was induced. Two wounds of 1 cm2 area were induced of which left side wounds served as the control and right side wounds were treated with GaAs laser at 4J/cm2 area for one minute continuously for four days. P. Nekha KrishnanP. T. DineshS. SooryadasReji VargheseM. PradeepDirector of Academics and Research, Kerala Veterinary and Animal Sciences Universityarticletype 2 diabetesstreptozotocingaas laserAnimal biochemistryQP501-801Science (General)Q1-390ENJournal of Veterinary and Animal Sciences, Vol 52, Iss 3, Pp 234-237 (2021)
institution DOAJ
collection DOAJ
language EN
topic type 2 diabetes
streptozotocin
gaas laser
Animal biochemistry
QP501-801
Science (General)
Q1-390
spellingShingle type 2 diabetes
streptozotocin
gaas laser
Animal biochemistry
QP501-801
Science (General)
Q1-390
P. Nekha Krishnan
P. T. Dinesh
S. Sooryadas
Reji Varghese
M. Pradeep
Healing of cutaneous wounds using GaAs laser in diabetic rat models
description Conventional treatment modalities usually fail to heal wounds in diabetic animals. Photomodulation of the wound bed using low-level laser has proved its efficacy in treating chronic wounds. Considering the fact that the majority of the diabetic wounds end up in amputation of affected part and reduce the quality of life of the patient, the present study was undertaken to find out the efficacy of gallium arsenide (GaAs) laser in the healing of full-thickness cutaneous wounds in type 2 diabetic rat models. The study was conducted in six adult male Wistar rats with an average body weight of 150 g in which hyperglycemia coexisting with hyperlipidemia was induced. Two wounds of 1 cm2 area were induced of which left side wounds served as the control and right side wounds were treated with GaAs laser at 4J/cm2 area for one minute continuously for four days.
format article
author P. Nekha Krishnan
P. T. Dinesh
S. Sooryadas
Reji Varghese
M. Pradeep
author_facet P. Nekha Krishnan
P. T. Dinesh
S. Sooryadas
Reji Varghese
M. Pradeep
author_sort P. Nekha Krishnan
title Healing of cutaneous wounds using GaAs laser in diabetic rat models
title_short Healing of cutaneous wounds using GaAs laser in diabetic rat models
title_full Healing of cutaneous wounds using GaAs laser in diabetic rat models
title_fullStr Healing of cutaneous wounds using GaAs laser in diabetic rat models
title_full_unstemmed Healing of cutaneous wounds using GaAs laser in diabetic rat models
title_sort healing of cutaneous wounds using gaas laser in diabetic rat models
publisher Director of Academics and Research, Kerala Veterinary and Animal Sciences University
publishDate 2021
url https://doaj.org/article/1f8b700c56ee40d7b4d7b04ea74fa3ca
work_keys_str_mv AT pnekhakrishnan healingofcutaneouswoundsusinggaaslaserindiabeticratmodels
AT ptdinesh healingofcutaneouswoundsusinggaaslaserindiabeticratmodels
AT ssooryadas healingofcutaneouswoundsusinggaaslaserindiabeticratmodels
AT rejivarghese healingofcutaneouswoundsusinggaaslaserindiabeticratmodels
AT mpradeep healingofcutaneouswoundsusinggaaslaserindiabeticratmodels
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