Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

Proximity labeling is used to map and discover proteins in specific subcellular compartments. Here the authors combine APEX-mediated proximity labeling with organic-aqueous phase separation to identify nuclear, nucleolar, and outer mitochondrial membrane RNA binding proteins.

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Autores principales:	Wei Qin, Samuel A. Myers, Dominique K. Carey, Steven A. Carr, Alice Y. Ting
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f90c53d41e84c3aa3ffc690b80be3f3
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spelling	oai:doaj.org-article:1f90c53d41e84c3aa3ffc690b80be3f32021-12-02T16:45:48ZSpatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery10.1038/s41467-021-25259-22041-1723https://doaj.org/article/1f90c53d41e84c3aa3ffc690b80be3f32021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25259-2https://doaj.org/toc/2041-1723Proximity labeling is used to map and discover proteins in specific subcellular compartments. Here the authors combine APEX-mediated proximity labeling with organic-aqueous phase separation to identify nuclear, nucleolar, and outer mitochondrial membrane RNA binding proteins.Wei QinSamuel A. MyersDominique K. CareySteven A. CarrAlice Y. TingNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Qin Samuel A. Myers Dominique K. Carey Steven A. Carr Alice Y. Ting Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
description	Proximity labeling is used to map and discover proteins in specific subcellular compartments. Here the authors combine APEX-mediated proximity labeling with organic-aqueous phase separation to identify nuclear, nucleolar, and outer mitochondrial membrane RNA binding proteins.
format	article
author	Wei Qin Samuel A. Myers Dominique K. Carey Steven A. Carr Alice Y. Ting
author_facet	Wei Qin Samuel A. Myers Dominique K. Carey Steven A. Carr Alice Y. Ting
author_sort	Wei Qin
title	Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
title_short	Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
title_full	Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
title_fullStr	Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
title_full_unstemmed	Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery
title_sort	spatiotemporally-resolved mapping of rna binding proteins via functional proximity labeling reveals a mitochondrial mrna anchor promoting stress recovery
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1f90c53d41e84c3aa3ffc690b80be3f3
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Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

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