Exosomes as Actively Targeted Nanocarriers for Cancer Therapy

Yan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shang...

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Autores principales:	Wang Y, Zhang Y, Cai G, Li Q
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	exosomes nanocarriers function tumor therapy Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1fa00d8817f940498eb37f83ffd03e1f
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spelling	oai:doaj.org-article:1fa00d8817f940498eb37f83ffd03e1f2021-12-02T10:18:26ZExosomes as Actively Targeted Nanocarriers for Cancer Therapy1178-2013https://doaj.org/article/1fa00d8817f940498eb37f83ffd03e1f2020-06-01T00:00:00Zhttps://www.dovepress.com/exosomes-as-actively-targeted-nanocarriers-for-cancer-therapy-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Yan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li Email qili@shutcm.edu.cnAbstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.Keywords: exosomes, nanocarriers, function, tumor therapyWang YZhang YCai GLi QDove Medical Pressarticleexosomesnanocarriersfunctiontumor therapyMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 15, Pp 4257-4273 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	exosomes nanocarriers function tumor therapy Medicine (General) R5-920
spellingShingle	exosomes nanocarriers function tumor therapy Medicine (General) R5-920 Wang Y Zhang Y Cai G Li Q Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
description	Yan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li Email qili@shutcm.edu.cnAbstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.Keywords: exosomes, nanocarriers, function, tumor therapy
format	article
author	Wang Y Zhang Y Cai G Li Q
author_facet	Wang Y Zhang Y Cai G Li Q
author_sort	Wang Y
title	Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_short	Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_full	Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_fullStr	Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_full_unstemmed	Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_sort	exosomes as actively targeted nanocarriers for cancer therapy
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/1fa00d8817f940498eb37f83ffd03e1f
work_keys_str_mv	AT wangy exosomesasactivelytargetednanocarriersforcancertherapy AT zhangy exosomesasactivelytargetednanocarriersforcancertherapy AT caig exosomesasactivelytargetednanocarriersforcancertherapy AT liq exosomesasactivelytargetednanocarriersforcancertherapy
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Exosomes as Actively Targeted Nanocarriers for Cancer Therapy

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