Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages...
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Nature Portfolio
2019
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oai:doaj.org-article:1fa1f8e4a2e2471cb5c4e489ad2725cc2021-12-02T15:35:30ZPhototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity10.1038/s41467-019-09081-52041-1723https://doaj.org/article/1fa1f8e4a2e2471cb5c4e489ad2725cc2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09081-5https://doaj.org/toc/2041-1723Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages in mice in vivo.Lena PetersIna WeidenfeldUwe KlemmAnita LoeschckeRobin WeihmannKarl-Erich JaegerThomas DrepperVasilis NtziachristosAndre C. StielNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q Lena Peters Ina Weidenfeld Uwe Klemm Anita Loeschcke Robin Weihmann Karl-Erich Jaeger Thomas Drepper Vasilis Ntziachristos Andre C. Stiel Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
description |
Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages in mice in vivo. |
format |
article |
author |
Lena Peters Ina Weidenfeld Uwe Klemm Anita Loeschcke Robin Weihmann Karl-Erich Jaeger Thomas Drepper Vasilis Ntziachristos Andre C. Stiel |
author_facet |
Lena Peters Ina Weidenfeld Uwe Klemm Anita Loeschcke Robin Weihmann Karl-Erich Jaeger Thomas Drepper Vasilis Ntziachristos Andre C. Stiel |
author_sort |
Lena Peters |
title |
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
title_short |
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
title_full |
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
title_fullStr |
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
title_full_unstemmed |
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
title_sort |
phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/1fa1f8e4a2e2471cb5c4e489ad2725cc |
work_keys_str_mv |
AT lenapeters phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT inaweidenfeld phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT uweklemm phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT anitaloeschcke phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT robinweihmann phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT karlerichjaeger phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT thomasdrepper phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT vasilisntziachristos phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity AT andrecstiel phototrophicpurplebacteriaasoptoacousticinvivoreportersofmacrophageactivity |
_version_ |
1718386520873762816 |