Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity

Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages...

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Autores principales: Lena Peters, Ina Weidenfeld, Uwe Klemm, Anita Loeschcke, Robin Weihmann, Karl-Erich Jaeger, Thomas Drepper, Vasilis Ntziachristos, Andre C. Stiel
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1fa1f8e4a2e2471cb5c4e489ad2725cc
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spelling oai:doaj.org-article:1fa1f8e4a2e2471cb5c4e489ad2725cc2021-12-02T15:35:30ZPhototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity10.1038/s41467-019-09081-52041-1723https://doaj.org/article/1fa1f8e4a2e2471cb5c4e489ad2725cc2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09081-5https://doaj.org/toc/2041-1723Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages in mice in vivo.Lena PetersIna WeidenfeldUwe KlemmAnita LoeschckeRobin WeihmannKarl-Erich JaegerThomas DrepperVasilis NtziachristosAndre C. StielNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lena Peters
Ina Weidenfeld
Uwe Klemm
Anita Loeschcke
Robin Weihmann
Karl-Erich Jaeger
Thomas Drepper
Vasilis Ntziachristos
Andre C. Stiel
Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
description Current optoacoustic probes for cancer imaging have limitations including background noise, long-term toxicity and scarce imaging depth in living tissue. Here the authors use Rhodobacter, purple bacteria rich in bacteriochlorophyll a, as an optoacoustic reporter to image tumor-associated macrophages in mice in vivo.
format article
author Lena Peters
Ina Weidenfeld
Uwe Klemm
Anita Loeschcke
Robin Weihmann
Karl-Erich Jaeger
Thomas Drepper
Vasilis Ntziachristos
Andre C. Stiel
author_facet Lena Peters
Ina Weidenfeld
Uwe Klemm
Anita Loeschcke
Robin Weihmann
Karl-Erich Jaeger
Thomas Drepper
Vasilis Ntziachristos
Andre C. Stiel
author_sort Lena Peters
title Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
title_short Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
title_full Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
title_fullStr Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
title_full_unstemmed Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
title_sort phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1fa1f8e4a2e2471cb5c4e489ad2725cc
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