MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

Abstract miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower number of airway generations, and a thicker m...

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Bibliographic Details
Main Authors: Naghmeh Khoshgoo, Robin Visser, Landon Falk, Chelsea A. Day, Dustin Ameis, Barbara M. Iwasiow, Fuqin Zhu, Arzu Öztürk, Sujata Basu, Molly Pind, Agnes Fresnosa, Mike Jackson, Vinaya Kumar Siragam, Gerald Stelmack, Geoffrey G. Hicks, Andrew J. Halayko, Richard Keijzer
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/1fa44ab5d33f4684b3412c079afd0d84
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