Association between Maternal Non-Coding Interferon-λ Polymorphisms and Congenital Zika Syndrome in a Cohort from Brazilian Northeast

Association between Maternal Non-Coding Interferon-λ Polymorphisms and Congenital Zika Syndrome in a Cohort from Brazilian Northeast

Congenital Zika syndrome (CZS) is characterized by a diverse group of congenital malformations induced by ZIKV infection during pregnancy. Type III interferons have been associated with placental immunity against ZIKV and restriction of vertical transmission in mice, and non-coding single-nucleotide...

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Autores principales: Átila Duque Rossi, Fabio Rueda Faucz, Adriana Melo, Girlene Souza de Azevedo, Paula Pezzuto, Ohanna Cavalcanti de Lima Bezerra, Fernanda Saloum de Neves Manta, Tamiris Azamor, Bruno Luiz Fonseca Schamber-Reis, Amilcar Tanuri, Milton Ozório Moraes, Renato Santana Aguiar, Constantine A. Stratakis, Cynthia Chester Cardoso
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Zika
type III interferon
polymorphism
congenital Zika syndrome
genetic susceptibility
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1fbefc8d57cb4b1ca2c49d02652c14c5
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