CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease

Phenotypic markers that overlap between ILC1 and NK populations have impacted the robust and specific analysis of these immune cell populations. Employing scRNA sequencing here the authors identify CD127+ CD94+ innate lymphoid cells that express granulysin and perforin and are expanded in patients w...

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Autores principales:	L. Krabbendam, B. A. Heesters, C. M. A. Kradolfer, N. J. E. Haverkate, M. A. J. Becker, C. J. Buskens, W. A. Bemelman, J. H. Bernink, H. Spits
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1fc6af1d913c45e8876e1267a084185f
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spelling	oai:doaj.org-article:1fc6af1d913c45e8876e1267a084185f2021-12-02T16:57:08ZCD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease10.1038/s41467-021-26187-x2041-1723https://doaj.org/article/1fc6af1d913c45e8876e1267a084185f2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26187-xhttps://doaj.org/toc/2041-1723Phenotypic markers that overlap between ILC1 and NK populations have impacted the robust and specific analysis of these immune cell populations. Employing scRNA sequencing here the authors identify CD127+ CD94+ innate lymphoid cells that express granulysin and perforin and are expanded in patients with Crohn’s disease.L. KrabbendamB. A. HeestersC. M. A. KradolferN. J. E. HaverkateM. A. J. BeckerC. J. BuskensW. A. BemelmanJ. H. BerninkH. SpitsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q L. Krabbendam B. A. Heesters C. M. A. Kradolfer N. J. E. Haverkate M. A. J. Becker C. J. Buskens W. A. Bemelman J. H. Bernink H. Spits CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
description	Phenotypic markers that overlap between ILC1 and NK populations have impacted the robust and specific analysis of these immune cell populations. Employing scRNA sequencing here the authors identify CD127+ CD94+ innate lymphoid cells that express granulysin and perforin and are expanded in patients with Crohn’s disease.
format	article
author	L. Krabbendam B. A. Heesters C. M. A. Kradolfer N. J. E. Haverkate M. A. J. Becker C. J. Buskens W. A. Bemelman J. H. Bernink H. Spits
author_facet	L. Krabbendam B. A. Heesters C. M. A. Kradolfer N. J. E. Haverkate M. A. J. Becker C. J. Buskens W. A. Bemelman J. H. Bernink H. Spits
author_sort	L. Krabbendam
title	CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
title_short	CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
title_full	CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
title_fullStr	CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
title_full_unstemmed	CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
title_sort	cd127+ cd94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with crohn’s disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1fc6af1d913c45e8876e1267a084185f
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CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease

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