Localisation of clozapine during experimental autoimmune encephalomyelitis and its impact on dopamine and its receptors

Localisation of clozapine during experimental autoimmune encephalomyelitis and its impact on dopamine and its receptors

Abstract Multiple sclerosis is a disease characterised by axonal demyelination in the central nervous system (CNS). The atypical antipsychotic drug clozapine attenuates experimental autoimmune encephalomyelitis (EAE), a mouse model used to study multiple sclerosis, but the precise mechanism is unkno...

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Autores principales: Katharina Robichon, Sven Sondhauss, T. William Jordan, Robert A. Keyzers, Bronwen Connor, Anne C. La Flamme
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1fc8228af1f0439d8a8f71c4d574ac28
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