Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves

Abstract Ruminants microbial consortium is responsible for ruminal fermentation, a process which converts fibrous feeds unsuitable for human consumption into desirable dairy and meat products, begins to establish soon after birth. However, it undergoes a significant transition when digestion shifts...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	S. J. Meale, S. C. Li, P. Azevedo, H. Derakhshani, T. J. DeVries, J. C. Plaizier, M. A. Steele, E. Khafipour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1fcd22a40d704df3b0f8d305437ad3a6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1fcd22a40d704df3b0f8d305437ad3a6
record_format	dspace
spelling	oai:doaj.org-article:1fcd22a40d704df3b0f8d305437ad3a62021-12-02T12:32:30ZWeaning age influences the severity of gastrointestinal microbiome shifts in dairy calves10.1038/s41598-017-00223-72045-2322https://doaj.org/article/1fcd22a40d704df3b0f8d305437ad3a62017-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00223-7https://doaj.org/toc/2045-2322Abstract Ruminants microbial consortium is responsible for ruminal fermentation, a process which converts fibrous feeds unsuitable for human consumption into desirable dairy and meat products, begins to establish soon after birth. However, it undergoes a significant transition when digestion shifts from the lower intestine to ruminal fermentation. We hypothesised that delaying the transition from a high milk diet to an exclusively solid food diet (weaning) would lessen the severity of changes in the gastrointestinal microbiome during this transition. β-diversity of ruminal and faecal microbiota shifted rapidly in early-weaned calves (6 weeks), whereas, a more gradual shift was observed in late-weaned calves (8 weeks) up to weaning. Bacteroidetes and Firmicutes were the most abundant ruminal phyla in pre- and post-weaned calves, respectively. Yet, the relative abundance of these phyla remained stable in faeces (P ≥ 0.391). Inferred gene families assigned to KEGG pathways revealed an increase in ruminal carbohydrate metabolism (P ≤ 0.009) at 9, compared to 5 weeks. Conversely, carbohydrate metabolism in faeces declined (P ≤ 0.002) following a change in weaning status (i.e., the shift from pre- to post-weaning). Our results indicate weaning later facilitates a more gradual shift in microbiota and could potentially explain the negative effects of early-weaning associated with feeding a high-plane of pre-weaning nutrition.S. J. MealeS. C. LiP. AzevedoH. DerakhshaniT. J. DeVriesJ. C. PlaizierM. A. SteeleE. KhafipourNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q S. J. Meale S. C. Li P. Azevedo H. Derakhshani T. J. DeVries J. C. Plaizier M. A. Steele E. Khafipour Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
description	Abstract Ruminants microbial consortium is responsible for ruminal fermentation, a process which converts fibrous feeds unsuitable for human consumption into desirable dairy and meat products, begins to establish soon after birth. However, it undergoes a significant transition when digestion shifts from the lower intestine to ruminal fermentation. We hypothesised that delaying the transition from a high milk diet to an exclusively solid food diet (weaning) would lessen the severity of changes in the gastrointestinal microbiome during this transition. β-diversity of ruminal and faecal microbiota shifted rapidly in early-weaned calves (6 weeks), whereas, a more gradual shift was observed in late-weaned calves (8 weeks) up to weaning. Bacteroidetes and Firmicutes were the most abundant ruminal phyla in pre- and post-weaned calves, respectively. Yet, the relative abundance of these phyla remained stable in faeces (P ≥ 0.391). Inferred gene families assigned to KEGG pathways revealed an increase in ruminal carbohydrate metabolism (P ≤ 0.009) at 9, compared to 5 weeks. Conversely, carbohydrate metabolism in faeces declined (P ≤ 0.002) following a change in weaning status (i.e., the shift from pre- to post-weaning). Our results indicate weaning later facilitates a more gradual shift in microbiota and could potentially explain the negative effects of early-weaning associated with feeding a high-plane of pre-weaning nutrition.
format	article
author	S. J. Meale S. C. Li P. Azevedo H. Derakhshani T. J. DeVries J. C. Plaizier M. A. Steele E. Khafipour
author_facet	S. J. Meale S. C. Li P. Azevedo H. Derakhshani T. J. DeVries J. C. Plaizier M. A. Steele E. Khafipour
author_sort	S. J. Meale
title	Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
title_short	Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
title_full	Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
title_fullStr	Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
title_full_unstemmed	Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
title_sort	weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1fcd22a40d704df3b0f8d305437ad3a6
work_keys_str_mv	AT sjmeale weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT scli weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT pazevedo weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT hderakhshani weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT tjdevries weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT jcplaizier weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT masteele weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves AT ekhafipour weaningageinfluencestheseverityofgastrointestinalmicrobiomeshiftsindairycalves
_version_	1718394025013149696

Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves

Ejemplares similares