CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis
Microsatellite genotyping is a common molecular method of for identification but current methods have restricted throughput. The authors demonstrate STR-Seq, which combines next generation sequencing with targetedin vitroCRISPR-Cas9 fragmentation to enable massively parallel analysis in the thousand...
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Autores principales: | GiWon Shin, Susan M. Grimes, HoJoon Lee, Billy T. Lau, Li C. Xia, Hanlee P. Ji |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1fd514e535d042ffa2a18a3e8a9b6a4c |
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