PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]

Penghui Wei, Fan Yang, Jianjun LiDepartment of Anesthesiology, Qilu Hospital of Shandong University (Qingdao), Qingdao 266035, People’s Republic of ChinaDear EditorRecently, we read with great interest the well-written review article published in the November 8, 2018 edition of th...

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Autores principales:	Wei P, Yang F, Li J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Postoperative Cognitive Dysfunction Preventive Strategies；Immunotherapy Neuroinflammation Systemic Immune Response Programmed Death-1 Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/1fd7baa5e26b44fb94cdd3f6f42c9888
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spelling	oai:doaj.org-article:1fd7baa5e26b44fb94cdd3f6f42c98882021-12-02T06:01:59ZPD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]1178-1998https://doaj.org/article/1fd7baa5e26b44fb94cdd3f6f42c98882019-04-01T00:00:00Zhttps://www.dovepress.com/pd-1-immune-checkpoint-blockade-may-be-viable-for-the-prevention-and-t-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Penghui Wei, Fan Yang, Jianjun LiDepartment of Anesthesiology, Qilu Hospital of Shandong University (Qingdao), Qingdao 266035, People’s Republic of ChinaDear EditorRecently, we read with great interest the well-written review article published in the November 8, 2018 edition of the Clinical Interventions in Aging by Kotekar and colleagues titled “Postoperative cognitive dysfunction – current preventive strategies”.1 The article elegantly addressed the current preventive strategies for postoperative cognitive dysfunction (POCD). The authors concluded that the best preventive strategies for POCD may involve early recognition and management of potential perioperative risk factors, such as intraoperative anesthetic monitoring of the depth of anesthesia, Enhanced Recovery After Surgery and a multidisciplinary collaboration. Furthermore, the authors proposed that pharmacological interventions may be effective preventative and therapeutic strategies to attenuate POCD.We appreciate the efforts of the authors and would like to present our opinion on the review.View the original paper by Kotekar and colleaguesWei PYang FLi JDove Medical PressarticlePostoperative Cognitive DysfunctionPreventive Strategies；ImmunotherapyNeuroinflammationSystemic Immune ResponseProgrammed Death-1GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 14, Pp 689-691 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Postoperative Cognitive Dysfunction Preventive Strategies；Immunotherapy Neuroinflammation Systemic Immune Response Programmed Death-1 Geriatrics RC952-954.6
spellingShingle	Postoperative Cognitive Dysfunction Preventive Strategies；Immunotherapy Neuroinflammation Systemic Immune Response Programmed Death-1 Geriatrics RC952-954.6 Wei P Yang F Li J PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
description	Penghui Wei, Fan Yang, Jianjun LiDepartment of Anesthesiology, Qilu Hospital of Shandong University (Qingdao), Qingdao 266035, People’s Republic of ChinaDear EditorRecently, we read with great interest the well-written review article published in the November 8, 2018 edition of the Clinical Interventions in Aging by Kotekar and colleagues titled “Postoperative cognitive dysfunction – current preventive strategies”.1 The article elegantly addressed the current preventive strategies for postoperative cognitive dysfunction (POCD). The authors concluded that the best preventive strategies for POCD may involve early recognition and management of potential perioperative risk factors, such as intraoperative anesthetic monitoring of the depth of anesthesia, Enhanced Recovery After Surgery and a multidisciplinary collaboration. Furthermore, the authors proposed that pharmacological interventions may be effective preventative and therapeutic strategies to attenuate POCD.We appreciate the efforts of the authors and would like to present our opinion on the review.View the original paper by Kotekar and colleagues
format	article
author	Wei P Yang F Li J
author_facet	Wei P Yang F Li J
author_sort	Wei P
title	PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
title_short	PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
title_full	PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
title_fullStr	PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
title_full_unstemmed	PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
title_sort	pd-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with pocd [letter]
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/1fd7baa5e26b44fb94cdd3f6f42c9888
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PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]

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