Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.
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Nature Portfolio
2016
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oai:doaj.org-article:1fdccc86530b44ceb8758d17f008c0d52021-12-02T15:35:02ZSingle-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli10.1038/ncomms125682041-1723https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d52016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12568https://doaj.org/toc/2041-1723Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.Mathew StracyMarcin JaciukStephan UphoffAchillefs N. KapanidisMarcin NowotnyDavid J. SherrattPawel ZawadzkiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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Science Q Mathew Stracy Marcin Jaciuk Stephan Uphoff Achillefs N. Kapanidis Marcin Nowotny David J. Sherratt Pawel Zawadzki Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
description |
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function. |
format |
article |
author |
Mathew Stracy Marcin Jaciuk Stephan Uphoff Achillefs N. Kapanidis Marcin Nowotny David J. Sherratt Pawel Zawadzki |
author_facet |
Mathew Stracy Marcin Jaciuk Stephan Uphoff Achillefs N. Kapanidis Marcin Nowotny David J. Sherratt Pawel Zawadzki |
author_sort |
Mathew Stracy |
title |
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
title_short |
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
title_full |
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
title_fullStr |
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
title_full_unstemmed |
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli |
title_sort |
single-molecule imaging of uvra and uvrb recruitment to dna lesions in living escherichia coli |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d5 |
work_keys_str_mv |
AT mathewstracy singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT marcinjaciuk singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT stephanuphoff singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT achillefsnkapanidis singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT marcinnowotny singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT davidjsherratt singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli AT pawelzawadzki singlemoleculeimagingofuvraanduvrbrecruitmenttodnalesionsinlivingescherichiacoli |
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