Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.

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Autores principales: Mathew Stracy, Marcin Jaciuk, Stephan Uphoff, Achillefs N. Kapanidis, Marcin Nowotny, David J. Sherratt, Pawel Zawadzki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d5
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spelling oai:doaj.org-article:1fdccc86530b44ceb8758d17f008c0d52021-12-02T15:35:02ZSingle-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli10.1038/ncomms125682041-1723https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d52016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12568https://doaj.org/toc/2041-1723Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.Mathew StracyMarcin JaciukStephan UphoffAchillefs N. KapanidisMarcin NowotnyDavid J. SherrattPawel ZawadzkiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mathew Stracy
Marcin Jaciuk
Stephan Uphoff
Achillefs N. Kapanidis
Marcin Nowotny
David J. Sherratt
Pawel Zawadzki
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
description Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.
format article
author Mathew Stracy
Marcin Jaciuk
Stephan Uphoff
Achillefs N. Kapanidis
Marcin Nowotny
David J. Sherratt
Pawel Zawadzki
author_facet Mathew Stracy
Marcin Jaciuk
Stephan Uphoff
Achillefs N. Kapanidis
Marcin Nowotny
David J. Sherratt
Pawel Zawadzki
author_sort Mathew Stracy
title Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
title_short Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
title_full Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
title_fullStr Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
title_full_unstemmed Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
title_sort single-molecule imaging of uvra and uvrb recruitment to dna lesions in living escherichia coli
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d5
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