Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling

Basal ganglia can both facilitate or inhibit movement through excitatory and inhibitory pathways; however whether these opposing signals are dynamically regulated during behavior is not known. Here the authors use multinucleus LFP recordings and electrical microstimulation in monkeys performing sacc...

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Autores principales:	Jay J. Jantz, Masayuki Watanabe, Ron Levy, Douglas P. Munoz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1fe66825acb84618a83a8459a80104a1
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id	oai:doaj.org-article:1fe66825acb84618a83a8459a80104a1
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spelling	oai:doaj.org-article:1fe66825acb84618a83a8459a80104a12021-12-02T14:42:22ZEvidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling10.1038/s41467-017-01023-32041-1723https://doaj.org/article/1fe66825acb84618a83a8459a80104a12017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01023-3https://doaj.org/toc/2041-1723Basal ganglia can both facilitate or inhibit movement through excitatory and inhibitory pathways; however whether these opposing signals are dynamically regulated during behavior is not known. Here the authors use multinucleus LFP recordings and electrical microstimulation in monkeys performing saccade based tasks to show task specific changes in the tonic weighting of these pathways.Jay J. JantzMasayuki WatanabeRon LevyDouglas P. MunozNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jay J. Jantz Masayuki Watanabe Ron Levy Douglas P. Munoz Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
description	Basal ganglia can both facilitate or inhibit movement through excitatory and inhibitory pathways; however whether these opposing signals are dynamically regulated during behavior is not known. Here the authors use multinucleus LFP recordings and electrical microstimulation in monkeys performing saccade based tasks to show task specific changes in the tonic weighting of these pathways.
format	article
author	Jay J. Jantz Masayuki Watanabe Ron Levy Douglas P. Munoz
author_facet	Jay J. Jantz Masayuki Watanabe Ron Levy Douglas P. Munoz
author_sort	Jay J. Jantz
title	Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
title_short	Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
title_full	Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
title_fullStr	Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
title_full_unstemmed	Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
title_sort	evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1fe66825acb84618a83a8459a80104a1
work_keys_str_mv	AT jayjjantz evidenceforataskdependentswitchinsubthalamonigralbasalgangliasignaling AT masayukiwatanabe evidenceforataskdependentswitchinsubthalamonigralbasalgangliasignaling AT ronlevy evidenceforataskdependentswitchinsubthalamonigralbasalgangliasignaling AT douglaspmunoz evidenceforataskdependentswitchinsubthalamonigralbasalgangliasignaling
_version_	1718389677118980096

Evidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling

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