The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
The bromodomain containing protein BRD9 has been reported to regulate chromatin remodeling and transcription. Here the authors reveal a role for BRD9 in homologous recombination by facilitating RAD51–RAD54 interaction.
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Nature Portfolio
2020
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oai:doaj.org-article:1fe7fc0084cc463b8cd922a57f50a3682021-12-02T14:47:29ZThe bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair10.1038/s41467-020-16443-x2041-1723https://doaj.org/article/1fe7fc0084cc463b8cd922a57f50a3682020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16443-xhttps://doaj.org/toc/2041-1723The bromodomain containing protein BRD9 has been reported to regulate chromatin remodeling and transcription. Here the authors reveal a role for BRD9 in homologous recombination by facilitating RAD51–RAD54 interaction.Qin ZhouJinzhou HuangChao ZhangFei ZhaoWootae KimXinyi TuYong ZhangSomaira NowsheenQian ZhuMin DengYuping ChenBo QinKuntian LuoBaohua LiuZhenkun LouRobert W. MutterJian YuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Qin Zhou Jinzhou Huang Chao Zhang Fei Zhao Wootae Kim Xinyi Tu Yong Zhang Somaira Nowsheen Qian Zhu Min Deng Yuping Chen Bo Qin Kuntian Luo Baohua Liu Zhenkun Lou Robert W. Mutter Jian Yuan The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| description |
The bromodomain containing protein BRD9 has been reported to regulate chromatin remodeling and transcription. Here the authors reveal a role for BRD9 in homologous recombination by facilitating RAD51–RAD54 interaction. |
| format |
article |
| author |
Qin Zhou Jinzhou Huang Chao Zhang Fei Zhao Wootae Kim Xinyi Tu Yong Zhang Somaira Nowsheen Qian Zhu Min Deng Yuping Chen Bo Qin Kuntian Luo Baohua Liu Zhenkun Lou Robert W. Mutter Jian Yuan |
| author_facet |
Qin Zhou Jinzhou Huang Chao Zhang Fei Zhao Wootae Kim Xinyi Tu Yong Zhang Somaira Nowsheen Qian Zhu Min Deng Yuping Chen Bo Qin Kuntian Luo Baohua Liu Zhenkun Lou Robert W. Mutter Jian Yuan |
| author_sort |
Qin Zhou |
| title |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| title_short |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| title_full |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| title_fullStr |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| title_full_unstemmed |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair |
| title_sort |
bromodomain containing protein brd-9 orchestrates rad51–rad54 complex formation and regulates homologous recombination-mediated repair |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/1fe7fc0084cc463b8cd922a57f50a368 |
| work_keys_str_mv |
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