Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

The heterochromatin compartment is key for genome stability and cell fate transitions. Here, by tracking the heterochromatin response to UV damage in real time, the authors reveal how heterochromatin features are preserved following a genotoxic stress challenge.

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Autores principales:	Anna Fortuny, Audrey Chansard, Pierre Caron, Odile Chevallier, Olivier Leroy, Olivier Renaud, Sophie E. Polo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1fe91a3f20614556b7143250a1c68e3b
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spelling	oai:doaj.org-article:1fe91a3f20614556b7143250a1c68e3b2021-12-02T16:45:30ZImaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance10.1038/s41467-021-22575-52041-1723https://doaj.org/article/1fe91a3f20614556b7143250a1c68e3b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22575-5https://doaj.org/toc/2041-1723The heterochromatin compartment is key for genome stability and cell fate transitions. Here, by tracking the heterochromatin response to UV damage in real time, the authors reveal how heterochromatin features are preserved following a genotoxic stress challenge.Anna FortunyAudrey ChansardPierre CaronOdile ChevallierOlivier LeroyOlivier RenaudSophie E. PoloNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna Fortuny Audrey Chansard Pierre Caron Odile Chevallier Olivier Leroy Olivier Renaud Sophie E. Polo Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
description	The heterochromatin compartment is key for genome stability and cell fate transitions. Here, by tracking the heterochromatin response to UV damage in real time, the authors reveal how heterochromatin features are preserved following a genotoxic stress challenge.
format	article
author	Anna Fortuny Audrey Chansard Pierre Caron Odile Chevallier Olivier Leroy Olivier Renaud Sophie E. Polo
author_facet	Anna Fortuny Audrey Chansard Pierre Caron Odile Chevallier Olivier Leroy Olivier Renaud Sophie E. Polo
author_sort	Anna Fortuny
title	Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
title_short	Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
title_full	Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
title_fullStr	Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
title_full_unstemmed	Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
title_sort	imaging the response to dna damage in heterochromatin domains reveals core principles of heterochromatin maintenance
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1fe91a3f20614556b7143250a1c68e3b
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Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

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