The tumour suppressor CCDC6 is involved in ROS tolerance and neoplastic transformation by evading ferroptosis

Coiled-coil domain containing 6 (CCDC6) is a tumour suppressor gene involved in apoptosis and DNA damage response. CCDC6 is known to be functionally impaired upon gene fusions, somatic mutations, and altered protein turnover in several tumours. Testicular germ cell tumours are among the most common...

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Autores principales: Francesco Morra, Francesco Merolla, Federica Zito Marino, Rosaria Catalano, Renato Franco, Paolo Chieffi, Angela Celetti
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/1febab4fea964416bdfa82e956fce2cc
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