Development of background-free tame fluorescent probes for intracellular live cell imaging

The success of a fluorescent dye as a molecular probe to monitor the intracellular activity of biomolecules depends on its physicochemical characteristics. Here, the authors use a predictive model to identify key features that allow them to design cell permeable, background-free fluorescent probes.

Guardado en:

Detalles Bibliográficos
Autores principales:	Samira Husen Alamudi, Rudrakanta Satapathy, Jihyo Kim, Dongdong Su, Haiyan Ren, Rajkumar Das, Lingna Hu, Enrique Alvarado-Martínez, Jung Yeol Lee, Christian Hoppmann, Eduardo Peña-Cabrera, Hyung-Ho Ha, Hee-Sung Park, Lei Wang, Young-Tae Chang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ffa76b518c2484e9d9435cbbf2eabe7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1ffa76b518c2484e9d9435cbbf2eabe7
record_format	dspace
spelling	oai:doaj.org-article:1ffa76b518c2484e9d9435cbbf2eabe72021-12-02T17:33:08ZDevelopment of background-free tame fluorescent probes for intracellular live cell imaging10.1038/ncomms119642041-1723https://doaj.org/article/1ffa76b518c2484e9d9435cbbf2eabe72016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11964https://doaj.org/toc/2041-1723The success of a fluorescent dye as a molecular probe to monitor the intracellular activity of biomolecules depends on its physicochemical characteristics. Here, the authors use a predictive model to identify key features that allow them to design cell permeable, background-free fluorescent probes.Samira Husen AlamudiRudrakanta SatapathyJihyo KimDongdong SuHaiyan RenRajkumar DasLingna HuEnrique Alvarado-MartínezJung Yeol LeeChristian HoppmannEduardo Peña-CabreraHyung-Ho HaHee-Sung ParkLei WangYoung-Tae ChangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Samira Husen Alamudi Rudrakanta Satapathy Jihyo Kim Dongdong Su Haiyan Ren Rajkumar Das Lingna Hu Enrique Alvarado-Martínez Jung Yeol Lee Christian Hoppmann Eduardo Peña-Cabrera Hyung-Ho Ha Hee-Sung Park Lei Wang Young-Tae Chang Development of background-free tame fluorescent probes for intracellular live cell imaging
description	The success of a fluorescent dye as a molecular probe to monitor the intracellular activity of biomolecules depends on its physicochemical characteristics. Here, the authors use a predictive model to identify key features that allow them to design cell permeable, background-free fluorescent probes.
format	article
author	Samira Husen Alamudi Rudrakanta Satapathy Jihyo Kim Dongdong Su Haiyan Ren Rajkumar Das Lingna Hu Enrique Alvarado-Martínez Jung Yeol Lee Christian Hoppmann Eduardo Peña-Cabrera Hyung-Ho Ha Hee-Sung Park Lei Wang Young-Tae Chang
author_facet	Samira Husen Alamudi Rudrakanta Satapathy Jihyo Kim Dongdong Su Haiyan Ren Rajkumar Das Lingna Hu Enrique Alvarado-Martínez Jung Yeol Lee Christian Hoppmann Eduardo Peña-Cabrera Hyung-Ho Ha Hee-Sung Park Lei Wang Young-Tae Chang
author_sort	Samira Husen Alamudi
title	Development of background-free tame fluorescent probes for intracellular live cell imaging
title_short	Development of background-free tame fluorescent probes for intracellular live cell imaging
title_full	Development of background-free tame fluorescent probes for intracellular live cell imaging
title_fullStr	Development of background-free tame fluorescent probes for intracellular live cell imaging
title_full_unstemmed	Development of background-free tame fluorescent probes for intracellular live cell imaging
title_sort	development of background-free tame fluorescent probes for intracellular live cell imaging
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1ffa76b518c2484e9d9435cbbf2eabe7
work_keys_str_mv	AT samirahusenalamudi developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT rudrakantasatapathy developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT jihyokim developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT dongdongsu developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT haiyanren developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT rajkumardas developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT lingnahu developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT enriquealvaradomartinez developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT jungyeollee developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT christianhoppmann developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT eduardopenacabrera developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT hyunghoha developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT heesungpark developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT leiwang developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging AT youngtaechang developmentofbackgroundfreetamefluorescentprobesforintracellularlivecellimaging
_version_	1718380049452761088

Development of background-free tame fluorescent probes for intracellular live cell imaging

Ejemplares similares