Peripheral vasoreactivity in acute ischemic stroke with hemiplegia

Abstract The association between vasomotor tone of the peripheral arteries and cerebral hemisphere function has not been established. This study analyzed the peripheral vasoreactivity of patients with acute ischemic stroke and hemiplegia using a modified Raynaud scan, which is a new technology for b...

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Autores principales:	Su Jeong Wang, Chan-Hyuk Lee, Hyun Goo Kang, Ko Woon Kim, Minjoo Kim, Hwan-Jeong Jeong, Byoung-Soo Shin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1ffdc901240c49858c259853928a4cb5
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spelling	oai:doaj.org-article:1ffdc901240c49858c259853928a4cb52021-12-02T13:44:15ZPeripheral vasoreactivity in acute ischemic stroke with hemiplegia10.1038/s41598-021-88050-92045-2322https://doaj.org/article/1ffdc901240c49858c259853928a4cb52021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88050-9https://doaj.org/toc/2045-2322Abstract The association between vasomotor tone of the peripheral arteries and cerebral hemisphere function has not been established. This study analyzed the peripheral vasoreactivity of patients with acute ischemic stroke and hemiplegia using a modified Raynaud scan, which is a new technology for blood flow measurement. In this retrospective case–control study, we examined patients with unilateral weakness consistent with ischemic lesions who underwent brain magnetic resonance imaging and modified Raynaud scanning within five days from the onset of symptoms. The modified Raynaud scan was used to quantify the radioactivity of the bilateral fingertips during rest and cooling-heating thermal stress conditions and estimate vasoreactivity based on the change in the blood amount per time under rest-thermal stress. The subjects were classified into the preserved and impaired groups based on their degrees of vasomotor reaction. Based on the modified Raynaud scanning, 37 (mean age = 69.1 ± 10.6) and 32 (mean age = 62.6 ± 11.8) subjects were allocated to the preserved and impaired groups, respectively. Binary logistic regression showed that the affected limb edema (odds ratio (OR) 6.15; confidence interval (CI) 1.40–26.97; p = 0.016) and anterior circulation (OR 3.68; CI 1.01–13.48; p = 0.049) were associated with impaired vasoreactivity. The modified Raynaud scans confirmed that central lesions in the anterior circulation with hemiparesis may influence the vasoreactivity of edematous peripheral arteries. These results may inform treatment and rehabilitation for stroke patients with hemiparesis.Su Jeong WangChan-Hyuk LeeHyun Goo KangKo Woon KimMinjoo KimHwan-Jeong JeongByoung-Soo ShinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Su Jeong Wang Chan-Hyuk Lee Hyun Goo Kang Ko Woon Kim Minjoo Kim Hwan-Jeong Jeong Byoung-Soo Shin Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
description	Abstract The association between vasomotor tone of the peripheral arteries and cerebral hemisphere function has not been established. This study analyzed the peripheral vasoreactivity of patients with acute ischemic stroke and hemiplegia using a modified Raynaud scan, which is a new technology for blood flow measurement. In this retrospective case–control study, we examined patients with unilateral weakness consistent with ischemic lesions who underwent brain magnetic resonance imaging and modified Raynaud scanning within five days from the onset of symptoms. The modified Raynaud scan was used to quantify the radioactivity of the bilateral fingertips during rest and cooling-heating thermal stress conditions and estimate vasoreactivity based on the change in the blood amount per time under rest-thermal stress. The subjects were classified into the preserved and impaired groups based on their degrees of vasomotor reaction. Based on the modified Raynaud scanning, 37 (mean age = 69.1 ± 10.6) and 32 (mean age = 62.6 ± 11.8) subjects were allocated to the preserved and impaired groups, respectively. Binary logistic regression showed that the affected limb edema (odds ratio (OR) 6.15; confidence interval (CI) 1.40–26.97; p = 0.016) and anterior circulation (OR 3.68; CI 1.01–13.48; p = 0.049) were associated with impaired vasoreactivity. The modified Raynaud scans confirmed that central lesions in the anterior circulation with hemiparesis may influence the vasoreactivity of edematous peripheral arteries. These results may inform treatment and rehabilitation for stroke patients with hemiparesis.
format	article
author	Su Jeong Wang Chan-Hyuk Lee Hyun Goo Kang Ko Woon Kim Minjoo Kim Hwan-Jeong Jeong Byoung-Soo Shin
author_facet	Su Jeong Wang Chan-Hyuk Lee Hyun Goo Kang Ko Woon Kim Minjoo Kim Hwan-Jeong Jeong Byoung-Soo Shin
author_sort	Su Jeong Wang
title	Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
title_short	Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
title_full	Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
title_fullStr	Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
title_full_unstemmed	Peripheral vasoreactivity in acute ischemic stroke with hemiplegia
title_sort	peripheral vasoreactivity in acute ischemic stroke with hemiplegia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1ffdc901240c49858c259853928a4cb5
work_keys_str_mv	AT sujeongwang peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT chanhyuklee peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT hyungookang peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT kowoonkim peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT minjookim peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT hwanjeongjeong peripheralvasoreactivityinacuteischemicstrokewithhemiplegia AT byoungsooshin peripheralvasoreactivityinacuteischemicstrokewithhemiplegia
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Peripheral vasoreactivity in acute ischemic stroke with hemiplegia

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