Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.

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Autores principales:	Alessandro Cicconi, Rekha Rai, Xuexue Xiong, Cayla Broton, Amer Al-Hiyasat, Chunyi Hu, Siying Dong, Wenqi Sun, Jennifer Garbarino, Ranjit S. Bindra, Carl Schildkraut, Yong Chen, Sandy Chang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ffe736cceae4b6a9ede6a1d1309b5e3
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spelling	oai:doaj.org-article:1ffe736cceae4b6a9ede6a1d1309b5e32021-12-02T14:42:32ZMicrocephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly10.1038/s41467-020-19674-02041-1723https://doaj.org/article/1ffe736cceae4b6a9ede6a1d1309b5e32020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19674-0https://doaj.org/toc/2041-1723Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.Alessandro CicconiRekha RaiXuexue XiongCayla BrotonAmer Al-HiyasatChunyi HuSiying DongWenqi SunJennifer GarbarinoRanjit S. BindraCarl SchildkrautYong ChenSandy ChangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alessandro Cicconi Rekha Rai Xuexue Xiong Cayla Broton Amer Al-Hiyasat Chunyi Hu Siying Dong Wenqi Sun Jennifer Garbarino Ranjit S. Bindra Carl Schildkraut Yong Chen Sandy Chang Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
description	Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.
format	article
author	Alessandro Cicconi Rekha Rai Xuexue Xiong Cayla Broton Amer Al-Hiyasat Chunyi Hu Siying Dong Wenqi Sun Jennifer Garbarino Ranjit S. Bindra Carl Schildkraut Yong Chen Sandy Chang
author_facet	Alessandro Cicconi Rekha Rai Xuexue Xiong Cayla Broton Amer Al-Hiyasat Chunyi Hu Siying Dong Wenqi Sun Jennifer Garbarino Ranjit S. Bindra Carl Schildkraut Yong Chen Sandy Chang
author_sort	Alessandro Cicconi
title	Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
title_short	Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
title_full	Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
title_fullStr	Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
title_full_unstemmed	Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
title_sort	microcephalin 1/brit1-trf2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1ffe736cceae4b6a9ede6a1d1309b5e3
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Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

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