Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Terminal bd oxidases endow bacterial pathogens with resistance to cellular stressors. The authors report the structure of E. coli bd-II type oxidase with the bound inhibitor aurachin D, providing a structural basis for the design of specifically binding antibiotics.

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Auteurs principaux: Antonia Grauel, Jan Kägi, Tim Rasmussen, Iryna Makarchuk, Sabrina Oppermann, Aurélien F. A. Moumbock, Daniel Wohlwend, Rolf Müller, Frederic Melin, Stefan Günther, Petra Hellwig, Bettina Böttcher, Thorsten Friedrich
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/20085e0d8d9048149ac18c44b6585ba4
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