Choroidal thinning in high myopia measured by optical coherence tomography

Yasushi Ikuno, Satoko Fujimoto, Yukari Jo, Tomoko Asai, Kohji NishidaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, JapanPurpose: To investigate the rate of choroidal thinning in highly myopic eyes.Patients and methods: A retrospective observational study of 37 eye...

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Autores principales:	Ikuno Y, Fujimoto S, Jo Y, Asai T, Nishida K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/20238f2f67b1411a87a25ff7b0991e88
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spelling	oai:doaj.org-article:20238f2f67b1411a87a25ff7b0991e882021-12-02T04:51:53ZChoroidal thinning in high myopia measured by optical coherence tomography1177-54671177-5483https://doaj.org/article/20238f2f67b1411a87a25ff7b0991e882013-05-01T00:00:00Zhttp://www.dovepress.com/choroidal-thinning-in-high-myopia-measured-by-optical-coherence-tomogr-a13056https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Yasushi Ikuno, Satoko Fujimoto, Yukari Jo, Tomoko Asai, Kohji NishidaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, JapanPurpose: To investigate the rate of choroidal thinning in highly myopic eyes.Patients and methods: A retrospective observational study of 37 eyes of 26 subjects (nine males and 17 females, mean age 39.6 ± 7.7 years) with high myopia but no pathologies who had undergone spectral domain optical coherence tomography and repeated the test 1 year later (1 ± 0.25 year) at Osaka University Hospital, Osaka, Japan. Patients older than 50 years with visual acuity worse than 20/40 or with whitish chorioretinal atrophy involving the macula were excluded. Two masked raters measured the choroidal thicknesses (CTs) at the foveda, 3 mm superiorly, inferiorly, temporally, and nasally on the images and averaged the values. The second examination was about 365 days after the baseline examination. The CT reduction per year (CTRPY) was defined as (CT 1 year after - baseline CT)/days between the two examinations × 365. The retinal thicknesses were also investigated.Results: The CTRPY at the fovea was −1.0 ± 22.0 µm (range –50.2 to 98.5) at the fovea, –6.5 ± 24.3 µm (range −65.8 to 90.2) temporally, –0.5 ± 22.3 µm (range –27.1 to 82.5) nasally, –9.7 ± 21.7 µm (range –40.1 to 60.1) superiorly, and –1.4 ± 25.5 µm (range –85.6 to 75.2) inferiorly. There were no significant differences in the CTRPY at each location (P = 0.34). The CT decreased significantly (P < 0.05) only superiorly. The superior CTRPY was negatively correlated with the axial length (P < 0.05). The retinal thickness at the fovea did not change. Stepwise analysis for CTRPY selected axial length (P = 0.04, R2 = 0.13) and age (P = 0.08, R2 = 0.21) as relevant factors.Conclusions: The highly myopic choroid might gradually thin and be affected by many factors. Location and axial length are key factors to regulate the rate of choroidal thinning in highly myopic eyes. Overall choroidal thickness was not found to change significantly. Longer follow-ups are needed.Keywords: high myopia, choroid, optical coherence tomography, ageIkuno YFujimoto SJo YAsai TNishida KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 889-893 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Ikuno Y Fujimoto S Jo Y Asai T Nishida K Choroidal thinning in high myopia measured by optical coherence tomography
description	Yasushi Ikuno, Satoko Fujimoto, Yukari Jo, Tomoko Asai, Kohji NishidaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, JapanPurpose: To investigate the rate of choroidal thinning in highly myopic eyes.Patients and methods: A retrospective observational study of 37 eyes of 26 subjects (nine males and 17 females, mean age 39.6 ± 7.7 years) with high myopia but no pathologies who had undergone spectral domain optical coherence tomography and repeated the test 1 year later (1 ± 0.25 year) at Osaka University Hospital, Osaka, Japan. Patients older than 50 years with visual acuity worse than 20/40 or with whitish chorioretinal atrophy involving the macula were excluded. Two masked raters measured the choroidal thicknesses (CTs) at the foveda, 3 mm superiorly, inferiorly, temporally, and nasally on the images and averaged the values. The second examination was about 365 days after the baseline examination. The CT reduction per year (CTRPY) was defined as (CT 1 year after - baseline CT)/days between the two examinations × 365. The retinal thicknesses were also investigated.Results: The CTRPY at the fovea was −1.0 ± 22.0 µm (range –50.2 to 98.5) at the fovea, –6.5 ± 24.3 µm (range −65.8 to 90.2) temporally, –0.5 ± 22.3 µm (range –27.1 to 82.5) nasally, –9.7 ± 21.7 µm (range –40.1 to 60.1) superiorly, and –1.4 ± 25.5 µm (range –85.6 to 75.2) inferiorly. There were no significant differences in the CTRPY at each location (P = 0.34). The CT decreased significantly (P < 0.05) only superiorly. The superior CTRPY was negatively correlated with the axial length (P < 0.05). The retinal thickness at the fovea did not change. Stepwise analysis for CTRPY selected axial length (P = 0.04, R2 = 0.13) and age (P = 0.08, R2 = 0.21) as relevant factors.Conclusions: The highly myopic choroid might gradually thin and be affected by many factors. Location and axial length are key factors to regulate the rate of choroidal thinning in highly myopic eyes. Overall choroidal thickness was not found to change significantly. Longer follow-ups are needed.Keywords: high myopia, choroid, optical coherence tomography, age
format	article
author	Ikuno Y Fujimoto S Jo Y Asai T Nishida K
author_facet	Ikuno Y Fujimoto S Jo Y Asai T Nishida K
author_sort	Ikuno Y
title	Choroidal thinning in high myopia measured by optical coherence tomography
title_short	Choroidal thinning in high myopia measured by optical coherence tomography
title_full	Choroidal thinning in high myopia measured by optical coherence tomography
title_fullStr	Choroidal thinning in high myopia measured by optical coherence tomography
title_full_unstemmed	Choroidal thinning in high myopia measured by optical coherence tomography
title_sort	choroidal thinning in high myopia measured by optical coherence tomography
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/20238f2f67b1411a87a25ff7b0991e88
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Choroidal thinning in high myopia measured by optical coherence tomography

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