Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.

<h4>Background and aims</h4>Liver fibrosis is a major cause of morbidity and mortality. It is characterised by excessive extracellular matrix (ECM) deposition from activated hepatic stellate cells (HSCs). Although potentially reversible, treatment remains limited. Understanding how ECM i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: James Pritchett, Varinder S Athwal, Emma Harvey, Katherine Martin, Jessica Llewellyn, Philip Ireland, Alexander Nicolaides, Martin J Humphries, Nicoletta Bobola, Neil A Hanley, Karen Piper Hanley
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/202462e452b44d6f83ef982a6e27c81e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!