Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natura...
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2021
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oai:doaj.org-article:2028f3a39a5c4516bfd1ae04c2a4f4992021-12-02T18:01:16ZTwo doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern10.1038/s41467-021-25167-52041-1723https://doaj.org/article/2028f3a39a5c4516bfd1ae04c2a4f4992021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25167-5https://doaj.org/toc/2041-1723Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natural infection.Donal T. SkellyAdam C. HardingJavier Gilbert-JaramilloMichael L. KnightStephanie LongetAnthony BrownSandra AdeleEmily AdlandHelen BrownMedawar Laboratory TeamTom TiptonLizzie StaffordAlexander J. MentzerSíle A. JohnsonAli AminiOPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical GroupTiong Kit TanLisa SchimanskiKuan-Ying A. HuangPramila RijalPITCH (Protective Immunity T cells in Health Care Worker) Study GroupC-MORE/PHOSP-C GroupJohn FraterPhilip GoulderChristopher P. ConlonKatie JefferyChristina DoldAndrew J. PollardAlex SigalTulio de OliveiraAlain R. TownsendPaul KlenermanSusanna J. DunachieEleanor BarnesMiles W. CarrollWilliam S. JamesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Donal T. Skelly Adam C. Harding Javier Gilbert-Jaramillo Michael L. Knight Stephanie Longet Anthony Brown Sandra Adele Emily Adland Helen Brown Medawar Laboratory Team Tom Tipton Lizzie Stafford Alexander J. Mentzer Síle A. Johnson Ali Amini OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group Tiong Kit Tan Lisa Schimanski Kuan-Ying A. Huang Pramila Rijal PITCH (Protective Immunity T cells in Health Care Worker) Study Group C-MORE/PHOSP-C Group John Frater Philip Goulder Christopher P. Conlon Katie Jeffery Christina Dold Andrew J. Pollard Alex Sigal Tulio de Oliveira Alain R. Townsend Paul Klenerman Susanna J. Dunachie Eleanor Barnes Miles W. Carroll William S. James Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
description |
Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natural infection. |
format |
article |
author |
Donal T. Skelly Adam C. Harding Javier Gilbert-Jaramillo Michael L. Knight Stephanie Longet Anthony Brown Sandra Adele Emily Adland Helen Brown Medawar Laboratory Team Tom Tipton Lizzie Stafford Alexander J. Mentzer Síle A. Johnson Ali Amini OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group Tiong Kit Tan Lisa Schimanski Kuan-Ying A. Huang Pramila Rijal PITCH (Protective Immunity T cells in Health Care Worker) Study Group C-MORE/PHOSP-C Group John Frater Philip Goulder Christopher P. Conlon Katie Jeffery Christina Dold Andrew J. Pollard Alex Sigal Tulio de Oliveira Alain R. Townsend Paul Klenerman Susanna J. Dunachie Eleanor Barnes Miles W. Carroll William S. James |
author_facet |
Donal T. Skelly Adam C. Harding Javier Gilbert-Jaramillo Michael L. Knight Stephanie Longet Anthony Brown Sandra Adele Emily Adland Helen Brown Medawar Laboratory Team Tom Tipton Lizzie Stafford Alexander J. Mentzer Síle A. Johnson Ali Amini OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group Tiong Kit Tan Lisa Schimanski Kuan-Ying A. Huang Pramila Rijal PITCH (Protective Immunity T cells in Health Care Worker) Study Group C-MORE/PHOSP-C Group John Frater Philip Goulder Christopher P. Conlon Katie Jeffery Christina Dold Andrew J. Pollard Alex Sigal Tulio de Oliveira Alain R. Townsend Paul Klenerman Susanna J. Dunachie Eleanor Barnes Miles W. Carroll William S. James |
author_sort |
Donal T. Skelly |
title |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
title_short |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
title_full |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
title_fullStr |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
title_full_unstemmed |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern |
title_sort |
two doses of sars-cov-2 vaccination induce robust immune responses to emerging sars-cov-2 variants of concern |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2028f3a39a5c4516bfd1ae04c2a4f499 |
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