Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natura...

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Autores principales: Donal T. Skelly, Adam C. Harding, Javier Gilbert-Jaramillo, Michael L. Knight, Stephanie Longet, Anthony Brown, Sandra Adele, Emily Adland, Helen Brown, Medawar Laboratory Team, Tom Tipton, Lizzie Stafford, Alexander J. Mentzer, Síle A. Johnson, Ali Amini, OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Pramila Rijal, PITCH (Protective Immunity T cells in Health Care Worker) Study Group, C-MORE/PHOSP-C Group, John Frater, Philip Goulder, Christopher P. Conlon, Katie Jeffery, Christina Dold, Andrew J. Pollard, Alex Sigal, Tulio de Oliveira, Alain R. Townsend, Paul Klenerman, Susanna J. Dunachie, Eleanor Barnes, Miles W. Carroll, William S. James
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2028f3a39a5c4516bfd1ae04c2a4f499
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spelling oai:doaj.org-article:2028f3a39a5c4516bfd1ae04c2a4f4992021-12-02T18:01:16ZTwo doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern10.1038/s41467-021-25167-52041-1723https://doaj.org/article/2028f3a39a5c4516bfd1ae04c2a4f4992021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25167-5https://doaj.org/toc/2041-1723Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natural infection.Donal T. SkellyAdam C. HardingJavier Gilbert-JaramilloMichael L. KnightStephanie LongetAnthony BrownSandra AdeleEmily AdlandHelen BrownMedawar Laboratory TeamTom TiptonLizzie StaffordAlexander J. MentzerSíle A. JohnsonAli AminiOPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical GroupTiong Kit TanLisa SchimanskiKuan-Ying A. HuangPramila RijalPITCH (Protective Immunity T cells in Health Care Worker) Study GroupC-MORE/PHOSP-C GroupJohn FraterPhilip GoulderChristopher P. ConlonKatie JefferyChristina DoldAndrew J. PollardAlex SigalTulio de OliveiraAlain R. TownsendPaul KlenermanSusanna J. DunachieEleanor BarnesMiles W. CarrollWilliam S. JamesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Donal T. Skelly
Adam C. Harding
Javier Gilbert-Jaramillo
Michael L. Knight
Stephanie Longet
Anthony Brown
Sandra Adele
Emily Adland
Helen Brown
Medawar Laboratory Team
Tom Tipton
Lizzie Stafford
Alexander J. Mentzer
Síle A. Johnson
Ali Amini
OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group
Tiong Kit Tan
Lisa Schimanski
Kuan-Ying A. Huang
Pramila Rijal
PITCH (Protective Immunity T cells in Health Care Worker) Study Group
C-MORE/PHOSP-C Group
John Frater
Philip Goulder
Christopher P. Conlon
Katie Jeffery
Christina Dold
Andrew J. Pollard
Alex Sigal
Tulio de Oliveira
Alain R. Townsend
Paul Klenerman
Susanna J. Dunachie
Eleanor Barnes
Miles W. Carroll
William S. James
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
description Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natural infection.
format article
author Donal T. Skelly
Adam C. Harding
Javier Gilbert-Jaramillo
Michael L. Knight
Stephanie Longet
Anthony Brown
Sandra Adele
Emily Adland
Helen Brown
Medawar Laboratory Team
Tom Tipton
Lizzie Stafford
Alexander J. Mentzer
Síle A. Johnson
Ali Amini
OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group
Tiong Kit Tan
Lisa Schimanski
Kuan-Ying A. Huang
Pramila Rijal
PITCH (Protective Immunity T cells in Health Care Worker) Study Group
C-MORE/PHOSP-C Group
John Frater
Philip Goulder
Christopher P. Conlon
Katie Jeffery
Christina Dold
Andrew J. Pollard
Alex Sigal
Tulio de Oliveira
Alain R. Townsend
Paul Klenerman
Susanna J. Dunachie
Eleanor Barnes
Miles W. Carroll
William S. James
author_facet Donal T. Skelly
Adam C. Harding
Javier Gilbert-Jaramillo
Michael L. Knight
Stephanie Longet
Anthony Brown
Sandra Adele
Emily Adland
Helen Brown
Medawar Laboratory Team
Tom Tipton
Lizzie Stafford
Alexander J. Mentzer
Síle A. Johnson
Ali Amini
OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group
Tiong Kit Tan
Lisa Schimanski
Kuan-Ying A. Huang
Pramila Rijal
PITCH (Protective Immunity T cells in Health Care Worker) Study Group
C-MORE/PHOSP-C Group
John Frater
Philip Goulder
Christopher P. Conlon
Katie Jeffery
Christina Dold
Andrew J. Pollard
Alex Sigal
Tulio de Oliveira
Alain R. Townsend
Paul Klenerman
Susanna J. Dunachie
Eleanor Barnes
Miles W. Carroll
William S. James
author_sort Donal T. Skelly
title Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
title_short Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
title_full Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
title_fullStr Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
title_full_unstemmed Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
title_sort two doses of sars-cov-2 vaccination induce robust immune responses to emerging sars-cov-2 variants of concern
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2028f3a39a5c4516bfd1ae04c2a4f499
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