Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.

Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.

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<h4>Background</h4>The detailed causes of death in non-ST-segment-elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those in ST-segment elevation myocardial infarction (STEMI).<h4>Methods</h4>The study population was 6,228 AMI patients wh...

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Autores principales: Yasuaki Takeji, Hiroki Shiomi, Takeshi Morimoto, Ko Yamamoto, Yukiko Matsumura-Nakano, Kazuya Nagao, Ryoji Taniguchi, Kyohei Yamaji, Tomohisa Tada, Eri Toda Kato, Yusuke Yoshikawa, Yuki Obayashi, Satoru Suwa, Moriaki Inoko, Natsuhiko Ehara, Toshihiro Tamura, Tomoya Onodera, Hiroki Watanabe, Mamoru Toyofuku, Kenji Nakatsuma, Hiroki Sakamoto, Kenji Ando, Yutaka Furukawa, Yukihito Sato, Yoshihisa Nakagawa, Kazushige Kadota, Takeshi Kimura, CREDO-Kyoto AMI Registry Wave-2 Investigators
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Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/2029195a3d974d06989dfc61cab90427
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spelling oai:doaj.org-article:2029195a3d974d06989dfc61cab904272021-12-02T20:12:57ZDifferences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.1932-620310.1371/journal.pone.0259268https://doaj.org/article/2029195a3d974d06989dfc61cab904272021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0259268https://doaj.org/toc/1932-6203<h4>Background</h4>The detailed causes of death in non-ST-segment-elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those in ST-segment elevation myocardial infarction (STEMI).<h4>Methods</h4>The study population was 6,228 AMI patients who underwent percutaneous coronary intervention (STEMI: 4,625 patients and NSTEMI: 1,603 patients). The primary outcome was all-cause death.<h4>Results</h4>Within 6 months after AMI, the adjusted mortality risk was not significantly different between NSTEMI patients and STEMI patients (HR: 0.83, 95%CI: 0.67-1.03, P = 0.09). Regarding the causes of death within 6 months after AMI, mechanical complications more frequently occurred in STEMI patients than in NSTEMI patients, while proportions of post resuscitation status on arrival and heart failure were higher in in NSTEMI patients than in STEMI patients. Beyond 6 months after AMI, the adjusted mortality risk of NSTEMI relative to STEMI was not significantly different. (HR: 1.04, 95%CI: 0.90-1.20, P = 0.59). Regarding causes of death beyond 6 months after AMI, almost half of deaths were cardiovascular causes in both groups, and breakdown of causes of death was similar between NSTEMI and STEMI.<h4>Conclusion</h4>The mortality risk within and beyond 6 months after AMI were not significantly different between STEMI patients and NSTEMI patients after adjusting confounders. Deaths due to post resuscitation status and heart failure were more frequent in NSTEMI within 6 months after AMI.Yasuaki TakejiHiroki ShiomiTakeshi MorimotoKo YamamotoYukiko Matsumura-NakanoKazuya NagaoRyoji TaniguchiKyohei YamajiTomohisa TadaEri Toda KatoYusuke YoshikawaYuki ObayashiSatoru SuwaMoriaki InokoNatsuhiko EharaToshihiro TamuraTomoya OnoderaHiroki WatanabeMamoru ToyofukuKenji NakatsumaHiroki SakamotoKenji AndoYutaka FurukawaYukihito SatoYoshihisa NakagawaKazushige KadotaTakeshi KimuraCREDO-Kyoto AMI Registry Wave-2 InvestigatorsPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0259268 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Yasuaki Takeji
Hiroki Shiomi
Takeshi Morimoto
Ko Yamamoto
Yukiko Matsumura-Nakano
Kazuya Nagao
Ryoji Taniguchi
Kyohei Yamaji
Tomohisa Tada
Eri Toda Kato
Yusuke Yoshikawa
Yuki Obayashi
Satoru Suwa
Moriaki Inoko
Natsuhiko Ehara
Toshihiro Tamura
Tomoya Onodera
Hiroki Watanabe
Mamoru Toyofuku
Kenji Nakatsuma
Hiroki Sakamoto
Kenji Ando
Yutaka Furukawa
Yukihito Sato
Yoshihisa Nakagawa
Kazushige Kadota
Takeshi Kimura
CREDO-Kyoto AMI Registry Wave-2 Investigators
Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
description <h4>Background</h4>The detailed causes of death in non-ST-segment-elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those in ST-segment elevation myocardial infarction (STEMI).<h4>Methods</h4>The study population was 6,228 AMI patients who underwent percutaneous coronary intervention (STEMI: 4,625 patients and NSTEMI: 1,603 patients). The primary outcome was all-cause death.<h4>Results</h4>Within 6 months after AMI, the adjusted mortality risk was not significantly different between NSTEMI patients and STEMI patients (HR: 0.83, 95%CI: 0.67-1.03, P = 0.09). Regarding the causes of death within 6 months after AMI, mechanical complications more frequently occurred in STEMI patients than in NSTEMI patients, while proportions of post resuscitation status on arrival and heart failure were higher in in NSTEMI patients than in STEMI patients. Beyond 6 months after AMI, the adjusted mortality risk of NSTEMI relative to STEMI was not significantly different. (HR: 1.04, 95%CI: 0.90-1.20, P = 0.59). Regarding causes of death beyond 6 months after AMI, almost half of deaths were cardiovascular causes in both groups, and breakdown of causes of death was similar between NSTEMI and STEMI.<h4>Conclusion</h4>The mortality risk within and beyond 6 months after AMI were not significantly different between STEMI patients and NSTEMI patients after adjusting confounders. Deaths due to post resuscitation status and heart failure were more frequent in NSTEMI within 6 months after AMI.
format article
author Yasuaki Takeji
Hiroki Shiomi
Takeshi Morimoto
Ko Yamamoto
Yukiko Matsumura-Nakano
Kazuya Nagao
Ryoji Taniguchi
Kyohei Yamaji
Tomohisa Tada
Eri Toda Kato
Yusuke Yoshikawa
Yuki Obayashi
Satoru Suwa
Moriaki Inoko
Natsuhiko Ehara
Toshihiro Tamura
Tomoya Onodera
Hiroki Watanabe
Mamoru Toyofuku
Kenji Nakatsuma
Hiroki Sakamoto
Kenji Ando
Yutaka Furukawa
Yukihito Sato
Yoshihisa Nakagawa
Kazushige Kadota
Takeshi Kimura
CREDO-Kyoto AMI Registry Wave-2 Investigators
author_facet Yasuaki Takeji
Hiroki Shiomi
Takeshi Morimoto
Ko Yamamoto
Yukiko Matsumura-Nakano
Kazuya Nagao
Ryoji Taniguchi
Kyohei Yamaji
Tomohisa Tada
Eri Toda Kato
Yusuke Yoshikawa
Yuki Obayashi
Satoru Suwa
Moriaki Inoko
Natsuhiko Ehara
Toshihiro Tamura
Tomoya Onodera
Hiroki Watanabe
Mamoru Toyofuku
Kenji Nakatsuma
Hiroki Sakamoto
Kenji Ando
Yutaka Furukawa
Yukihito Sato
Yoshihisa Nakagawa
Kazushige Kadota
Takeshi Kimura
CREDO-Kyoto AMI Registry Wave-2 Investigators
author_sort Yasuaki Takeji
title Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
title_short Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
title_full Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
title_fullStr Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
title_full_unstemmed Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction.
title_sort differences in mortality and causes of death between stemi and nstemi in the early and late phases after acute myocardial infarction.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/2029195a3d974d06989dfc61cab90427
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