NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia.
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy with few available targeted therapies. We previously reported that the phosphatase calcineurin (Cn) is required for LIC (leukemia Initiating Capacity) potential of T-ALL pointing to Cn as an interesting therapeutic target. Calci...
Guardado en:
Autores principales: | Claire Catherinet, Diana Passaro, Stéphanie Gachet, Hind Medyouf, Anne Reynaud, Charlène Lasgi, Jacques Ghysdael, Christine Tran Quang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2035fe1092774cfca12dbb1b405d0995 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival
por: Wenbin Zhong, et al.
Publicado: (2016) -
Therapeutic developments in acute lymphoblastic leukemia
por: MacKenzie A, et al.
Publicado: (2012) -
Profound leukemia cutis in a patient with relapsed T-cell acute lymphoblastic leukemia
por: Ambika Nohria, BA, et al.
Publicado: (2021) -
FEATURES OF IMMUNE CELLS IN ACUTE LYMPHOBLASTIC LEUKEMIA
por: O. V. Smirnova, et al.
Publicado: (2014) -
Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells
por: Vincent Fregona, et al.
Publicado: (2021)